Abstract:Objective: To investigate the difference in imaging features of renal clear cell carcinoma and renal papillary carcinoma with MRI, and to improve the diagnostic accuracy. Methods: Thirty-six cases of renal cell cancer from April 2011 to June 2013 in our hospital were confirmed pathologically and all of them had routine and enhanced MRI. The imaging features of these 36 cases were analysed retrospectively, their characteristics and differences were summarized. Results: In 36 cases of renal cell carcinoma, 31 cases were of clear cell carcinoma(32 lesions), 5 cases were of renal papillary carcinoma(5 lesions). Renal clear carcinoma and renal papillary carcinoma had nearly similar imaging features on plain MRI scans, most lesions were inhomogeneous: most of the renal clear carcinoma showed moderate and low signal on T1WI and most of the cases showed mixed signal on T2WI, most of the renal papillary carcinoma showed mixed signal both on T1WI and T2WI. On enhanced MRI, renal clear carcinoma were mainly moderate obviously and significantly enhanced in the cortical phase, and rapidly decline thereafter; renal papillary carcinoma were mainly mildly to moderately enhanced. Both of them showed heterogeneous enhancement, due to bleeding, necrosis and cystic degeneration within the tumor. Conclusion: MRI has important value, especially enhanced MRI in the differential diagnosis between renal clear cell carcinoma and renal papillary carcinoma.