Abstract：Objective: To determine the mechanism and influencing factors of crossed cerebellar diaschisis(CCD) observed in acute stroke with MR perfusion weighted imaging(PWI). Methods: Collections of PWI and diffusion weighted image(DWI) information of 41 patients, infarct volume on DWI and cerebral blood flow(CBF), cerebral blood volume(CBV), time to peak(TTP) and mean transit time(MTT) of the contralateral cerebellum were comparatively analyzed with those of the opposite healthy hemicerebrum and hemicerebellum. Results: Infarct volume on DWI in the CCD patients are significantly larger than that of the non-CCD patients(P<0.05). Of the CCD patients, CBF of the contralateral cerebellum is substantially reducted compared to that of the opposite hemicerebellum(P<0.05), TTP of the contralateral cerebellum is substantially prolonged than that of the opposite hemicerebellum(P<0.05), but there is not statistically significant changes in CBF and MTT between the two hemicerebellum(P>0.05). Conlusion: PWI is useful for studying the occurring and the influencing factor of CCD after supratentorial infarct.
2013, Vol. 24 
