Detection of Gamna-Gandy bodies in the spleen with SWI: compared with T1WI, T2WI, T2*WI
TAO Ran1, CUI Jin-guo1, ZHOU Xiang-jun2, TIAN Fu-cun2, CONG Wei2, ZHANG Jiu-quan3, WANG Jian3
1. Department of Radiology, Bethune International Peace Hospital of People’s Liberty Army, Shijiazhuang 050082, China;2. Hospital of 66172 Troops of People’s Liberty Army, Shijiazhuang 050082, China;3. Department of Radiology, Southwest Hospital, Third Military Medical University, Chongqing 400038, China
Abstract：Objective: To evaluate the role of abdominal susceptibility weighted imaging(SWI) in the detection of Gamna-Gandy bodies(GGBs) in the spleens of patients with portal hypertension. Materials and Methods: T1WI, T2WI, T2*WI and SWI were performed in 135 patients with portal hypertension. Two radiologists analyzed all the MRI data. The number of patients with GGB in the spleen were determined in four MRI sequences, and the numbers of GGBs were counted in GGB-positive patients. Results: Of the 135 patients with portal hypertension, 51 were GGB positive on SWI, and 17, 15, and 38 were positive on T1WI, T2WI and T2*WI, respectiely. Mean GGB numbers on T1WI, T2WI, T2*WI and SWI were 11.1±9.9, 5.4±5.5, 28.3±25.5, and 40.9±28.4, respectively. The GGB detection rate was significantly greater by SWI than by T1WI, T2WI and T2*WI(χ2=35.69, P<0.05). The number of GGBs detected was significantly greater by SWI than by T1WI, T2WI and T2*WI(P<0.05). Conclusion: SWI is the most sensitive method for detecting GGBs in spleen in patients with portal hypertension.
2013, Vol. 24 
