Abstract:Objective: To explore the feasibility of detecting parotid gland and submaxillary gland’s stiffness by shear wave elastography(SWE) and establish a reference range of Young’s modulus in healthy adult. Methods: There were 820 healthy volunteers underwent SWE in parotid gland and submaxillary gland. The difference of Young’s modulus in bilateral parotid and submaxillary gland, the values in different sex and age groups were also compared. Results: The differences of Young’s modulus between two sides of parotid gland and submaxillary gland has no statistically significant(P>0.05); the differences of Young’s modulus of parotid gland between different sex groups has statistical significance(P>0.05) but no statistical significance in submaxillary gland(P>0.05); The differences of Young’s modulus in parotid gland and submaxillary gland between different age groups has no statistical significance(P>0.05). Conclusion: SWE can be successfully applied to assess parotid gland and submaxillary gland’s stiffness and can provide valuable information for diagnosis.