Application value of combined dynamic contrast-enhanced MR imaging and diffusion-weighted MR imaging inmagnetic resonance mammography BI-RADS category 3-5 breast mass lesions
WANG Fei, BAO Ke-zhi, ZHU Juan, YANG Qing
Department of MRI, the Affiliated Anqing Hospital of Anhui Medical University, Anqing Anhui 246003, China
Abstract：Objective: To evaluate the diagnostic value of conventional MR mammography(MRM) combined with dynamic contrast-enhanced(DCE) MR imaging, and diffusion-weighted MR imaging(DWI) in the diagnosis and differential diagnosis of BI-RADS category 3-5 breast lesions. Methods: In 118 cases diagnosed as BI-RADS category 3-5 mass lesions, tumor morphology, hemodynamics of the masses and apparent diffusion coefficient(ADC) value were analysed retrospectively. Sensitivity, specificity, positive predictive value(PPV), negative predictive value(NPV) and accuracy were calculated. Results: In DCE-MRI, irregular and lobular shape, irregular and speculated margins, rim enhancement, early contrast-enhanced rate more than 100% and washout time-intensity curve(TIC) were the indicators of malignancy. The optimal threshold of 1.25×10-3mm2/s from receiver operating characteristic(ROC) curve, and have better diagnosis values(>0.900). The combined application provide sensitivity, specificity, PPV, NPV and accuracy were 90.4%, 91.4%, 96.2%, 80% and 90.7%. Conclusion: Conventional MRI combined with DCE-MRI and DWI were helpful to improve the diagnostic specificity and accuracy of BI-RADS category 3-5 breast mass lesions.
2013, Vol. 24 
