Abstract：Objective: To evaluate the usefulness of coefficient variance(CV) of apparent diffusion coefficient(ADC) value in differentiating pancreatic carcinoma from focal pancreatitis. Methods: Diffusion weighted MR data were obtained from 28 patients of pancreatic carcinoma and 7 patients of focal pancreatitis. The mean value(x) and standard deviation(s) of ADC value in every lesion were measured. The CV of the lesion was defined as CV＝s/x. The x values and CVs were compared between groups using Student’s t test. Result: The mean value of pancreatic carcinoma was 1.46±0.29, and the mean value of focal pancreatitis was 1.58±0.28. There were no obvious differences between the mean value of pancreatic carcinoma and focal pancreatitis(t=1.02, P=0.32). CV of pancreatic carcinoma was 0.16±0.06, and CV of focal pancreatitis was 0.10±0.04. CV of pancreatic carcinoma was significantly higher than that of focal pancreatitis(t=2.44, P=0.02). Conclusion: The CVs of ADC values in lesions were more useful than that of mean value to distinguish pancreatic carcinoma and focal pancreatitis.
2014, Vol. 25 
