Abstract：Objective: To compare the image quality(IQ) of different contrast materials(CM) injection protocols with low identical iodine delivery rate(IDR) for low-dose coronary CT angiography(CCTA) with iterative reconstruction(IR) technique. Methods: Ninety consecutive patients who underwent prospective electrocardiogram-CCTA on a 256-MDCT scanner were randomized to three groups: group A, which received CM(350 mgI/mL), was scanned by using the conventional tube output(120 kV) with filtered back projection(FBP). Group B which received CM(350 mgI/mL) and group C which received CM(270 mgI/mL) had identical IDR adapted to body mass index and weight, and scanned by 100 kV with iDOSE4 level 4. The subjective IQ, objective IQ, radiation dose and iodine load were compared among the three groups. Results: There were no significant differences in the image noise, contrast-to-noise ratio and attenuation of coronary among these three groups. Group B and C had good scores of the subjective IQ(≥3), and it could satisfy the clinical use. There was no significant difference of lumen contrast between group B and C. No significant differences of sharpness, subjective noise, and acceptability of images were observed, but the contrast dose of group A was significantly higher than group B and C. Mean iodine load of group A were 36.9%～39.6% higher than group B and C, and there was no difference between group B and C. The effective radiation dose of group B and C was 37.9% lower than group A, and there was no difference between group B and C. Conclusions: Equivalent and adequate diagnostic IQ can be achieved by using different iodine-concentration contrast materials(270 mgI/mL and 350 mgI/mL) when the IDR were kept identical in low-dose 256-MDCT coronary angiography with iDOSE4 level 4, compared with the IQ by using conventional tube output and FBP.
余 美，马 跃，王玉科，向纪卉，杨奕婧，侯 阳. 不同低对比剂注射方案对冠状动脉CTA图像质量影响的初步研究[J]. 中国临床医学影像杂志, 2015, 26(11): 779-783.
YU Mei, MA Yue, WANG Yu-ke, XIANG Ji-hui, YANG Yi-jing, HOU Yang. Comparison of image quality among different low dose contrast materials injection protocols in#br# coronary CT angiography. JOURNAL OF CHINA MEDICAL IMAGING, 2015, 26(11): 779-783.
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