磁敏感加权成像测量脑内血肿体积初步研究

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摘要目的：探讨磁敏感加权成像（Susceptibility weighted imaging，SWI）对脑内血肿体积测量的准确性。方法：回顾性分析70例脑出血（Intracerebral hemorrhage，ICH）病人，分别测量CT、常规MRI及SWI血肿体积，超急性期和急性期以CT测量数据作为标准体积，亚急性期以T1WI测量数据作为标准体积，并与同期SWI 融合图血肿体积比较并计算平均差异率，慢性期血肿不做体积测量。结果：70例ICH病人，SWI 对血肿检出率为100%，16例急性期血肿的SWI体积均大于CT体积，平均差异率为192.55%，且满足CT血肿体积=0.6×SWI血肿体积线性回归方程（Spearman’s相关系数=0.964，P<0.001），20例亚急性早期血肿和20例亚急性晚期血肿SWI体积均大于T1WI体积，平均差异率分别为101.66%、82.73%，以上差异均具有统计学意义（Z= -3.516，-3.921，-3.920，P<0.05）。结论：SWI识别不同时期血肿的敏感性均较高，但SWI对血肿体积具有高估倾向，尤其在急性期，CT血肿体积=0.6×SWI血肿体积线性方程，可以作为指导临床制定诊疗决策和监测预后的一项参考指标。

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	俞翔1
	刘筠2
	许亮2
	施逸兴3

关键词 ：脑出血, 血肿, 磁共振成像

Abstract：Objective: To investigate the efficacy of susceptibility weighted imaging(SWI) for measuring intracerebral hematoma volume. Methods: Seventy patients with intracerebral hemorrhage(ICH) were included in this research. The hematoma volume were measured on CT, conventional MRI and SWI, respectively. Standard hematoma volume was determined in hyperacute, acute phase on CT and subacute on T1WI. Compare the hematoma volume on SWI with CT or T1WI, except for chronic phase. Results: The detectable rate for ICH by SWI was 100%. Hematoma volume of 16 acute, 20 early subacute and 20 late subacute phase on SWI were larger than CT and T1WI counterparts and average difference rate were 192.55%, 101.66%, 82.73%, respectively. There were significant statistical difference among hematoma volume of different phases(Z=-3.516, -3.921, -3.920, P<0.05). A linear relationship defined by CT hematoma volume=0.6×SWI hematoma volume(Spearman’s correlation coefficient=0.964, P<0.001) was derived in acute phase. Conclusion: SWI is sensitive to intracerebral hematoma in different phases. However, SWI exists an overestimate tendency for hematoma volume, notably in acute phase. A simple mathematical conversion model has been developed: CT hematoma volume=0.6×SWI hematoma volume. This formula can be contribute to make clinical projects and monitor prognosis in an individual patient.

Key words： Cerebral hemorrhage Hematoma Magnetic resonace imaging

收稿日期: 2015-07-15

PACS:	Ｒ743.34
	Ｒ445.2

通讯作者: 刘筠

作者简介: 俞翔（1990-），男，河北廊坊人，在读硕士研究生。E-mail：cxksqiqi2013@163.com

引用本文:

俞翔1，刘筠2，许亮2，施逸兴3. 磁敏感加权成像测量脑内血肿体积初步研究[J]. 中国临床医学影像杂志, 2016, 27(2): 82-86.
YU Xiang1, LIU Jun2, XU Liang2, SHI Yi-xing3. Primary study for measuring intracerebral hematoma volume on SWI. JOURNAL OF CHINA MEDICAL IMAGING, 2016, 27(2): 82-86.

链接本文:

http://www.jccmi.com.cn/CN/ 或 http://www.jccmi.com.cn/CN/Y2016/V27/I2/82

[1]Brunkhorst R, Foerch C. What causes hematoma enlargement in lobar intracerebral hemorrhage?: novel insights from a genetic study[J]. Stroke, 2012, 43(6): 1458-1459.
[2]Allkemper T, Tombach B, Schwindt W, et al. Acute and subacute intracerebral hemorrhages: comparison of MR imaging at 1.5 and 3.0 T-initial experience[J]. Radiology, 2004, 232(3): 874-881.
[3]Naik D, Viswamitra S, Kumar AA, et al. Susceptibility weighted magnetic resonance imaging of brain: A multifaceted powerful sequence that adds to understanding of acute stroke[J]. Ann Indian Acad Neurol, 2014, 17(1): 58-61.
[4]Santhosh K, Kesavadas C, Thomas B, et al. Susceptibility weighted imaging: a new tool in magnetic resonance imaging of stroke[J]. Clin Radiol, 2009, 64(1): 74-83.
[5]Chalela JA, Kidwell CS, Nentwich LM, et al. Magnetic resonance imaging and computed tomography in emergency assessment of patients with suspected acute stroke: a prospective comparison[J]. Lancet, 2007, 369(9558): 293-298.
[6]赵开军，沈建康. 颅内血肿体积评估方法的影像和临床进展[J]. 中华神经外科疾病研究杂志，2010，9（4）：376-378.
[7]Zhao K, Liu Y, Zhang R, et al. A precise, simple, convenient and new method for estimation of intracranial hematoma volume-the formula 2/3[J]. Neurol Res, 2009, 31(10): 1031-1036.
[8]Keep RF, Hua Y, Xi G. Intracerebral haemorrhage: mechanisms of injury and therapeutic targets[J]. Lancet Neurol, 2012, 11(8): 720-731.
[9]Rodriguez-Luna D, Muchada M, Pineiro S, et al. Potential Blood Pressure Thresholds and Outcome in Acute Intracerebral Hemorrhage[J]. Eur Neurol, 2014, 72(3-4): 203-208.
[10]田亚楠，范敬争，李冠武，等. SWI评价大鼠脑出血模型血肿演变进程的实验研究[J]. 中国中西医结合影像学杂志，2014，12（1）：14-17.
[11]Morgenstern LB, Hemphill JC, Anderson C, et al. Guidelines for the Management of Spontaneous Intracerebral Hemorrhage: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association[J]. Stroke, 2010, 41(9): 2108-2129.
[12]Dammann P, Asgari S, Bassiouni H, et al. Spontaneous cerebellar hemorrhage-experience with 57 surgically treated patients and review of the literature[J]. Neurosurg Review, 2011, 34(1): 77-86.
[13]Zimmerman RD, Maldjian JA, Brun NC, et al. Radiologic estimation of hematoma volume in intracerebral hemorrhage trial by CT scan[J]. Am J Neuroradiol, 2006, 27(3): 666-670.
[14]杜万萍，谭利华，翟宁，等. 颅内血肿体积个人计算机测量方法[J]. 中南大学学报，2011，36（1）：84-87.
[15]Tang MY, Chen TW, Zhang XM, et al. GRE T2*-weighted MRI: principles and clinical applications[J]. Biomed Res Int, 2014, 2014(4): 1-12.
[16]Burgess RE, Warach S, Schaewe TJ, et al. Development and validation of a simple conversion model for comparison of intracerebral hemorrhage volumes measured on CT and gradient recalled echo MRI[J]. Stroke, 2008, 39(7): 2017-2020.
[17]王丽娟，刘玉波，王光彬. 磁敏感加权成像原理概述[J]. 磁共振成像，2010，1（3）：227-230.