Abstract：Objective: To explore the usual and unusual imaging appearances of giant cell tumor(GCT) in the mobile spine so as to improve the understanding of GCT. Methods: Sixty-two patients with GCT of mobile spine confirmed by pathological examinations were retrospectively analyzed and imaging appearances were summarized. Results: Forty-eight cases(77.4%) were located in the vertebral body and 14 cases(22.60%) located in the attachment of vertebra among 62 cases. Tumors located in cervical(21 cases), cervical-thoracic(4 cases), thoracic(25 cases) and lumbar(12 cases) spine. Adjacent three vertebral body or attachments were involved in 8 cases(12.9%). Thirty-four cases showed swelling bone destruction, 12 cases(19.35%) of the visible hardening ring, 23 cases(37.1%) with remaining bone crest, 6 cases of tumor edge with calcification or ossification, 8 cases with a huge mass lesion formation. Thirty-four tumors showed iso-intensity or low signal intensity, 23 with heterogeneous signal intensity and 3 with hyperintensity on T2WI and 11 cases had liquid level formation. Forty-five cases showed obvious enhancement, accounting for 72.6%. Six and 11 cases showed moderate and mild enhancement, accounting for 9.7% and 17.7% respectively. Uniform enhancement was in 23 cases, which accounted for only 37.1% among 62 cases of CT and MRI enhancement examinations. Conclusion: It is rare for GCT in the mobile spine to be located in the attachments or involve multiple vertebral bodies. Sclerosis rim around the tumor or calcification ossification is rare. Disproportionate huge mass formation and bone damage is rare. T2WI mainly shows low or mixed signals and high signal is rare. Tumor blood supply is relatively abundant with medium or obvious enhancement and mild enhancement is rare.
张立华，袁慧书. 可动脊柱骨巨细胞瘤的常见及少见影像表现分析[J]. 中国临床医学影像杂志, 2016, 27(2): 123-126.
ZHANG Li-hua, YUAN Hui-shu. Imaging analysis of usual and unusual imaging appearances of giant cell tumor in the mobile spine. JOURNAL OF CHINA MEDICAL IMAGING, 2016, 27(2): 123-126.
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