Quantitative assessment of left ventricular volume and systolic function using real-time three-dimensional echocardiography in late-stage liver cirrhosis
XU Hui, YANG Xiao-ying, WU Xiao-li, WANG Run-lan, MEI Li
Department of Ultrasound, the First Hospital of Jilin University, Changchun 130021, China
Abstract：Objective: To explore the value of real-time three-dimensional echocardiography(RT-3DE) in evaluating left ventricular volume and systolic function in late-stage liver cirrhosis. Methods: Thirty-two patients with late-stage liver cirrhosis and twenty healthy volunteers were enrolled in this study. Full volume RT-3DE was performed. The 17-segmental time-volume curves and left ventricular end-diastolic volume(EDV), end-systolic volume(ESV) and ejection fraction(EF) were obtained by the online Qlab software. The time to minimal systolic volume in each segment(Tmsv) was taken to derive the following indexes: Tmsv16-SD, Tmsv12-SD, Tmsv6-SD, Tmsv16-Dif, Tmsv12-Dif and Tmsv6-Dif, which meant the standard deviation or the maximal difference of Tmsv among the 16, 12 and 6 segments of the left ventricle respectively. The software also provided with each of the above parameters as a percentage of the cardiac cycle: Tmsv16-SD%, Tmsv12-SD%， Tmsv6-SD%, Tmsv16-Dif%, Tmsv12-Dif% and Tmsv6-Dif%. Results: EDV, ESV and EF of left ventricle: there were no significant differences between the two groups(P>0.05), Tmsv16-SD, Tmsv12-SD, Tmsv16-Dif, Tmsv12-Dif, Tmsv16-SD%, Tmsv12-SD%, Tmsv16-Dif%, Tmsv12-Dif%: were significantly higher in late-stage liver cirrhosis than those in the control group(P<0.05), Tmsv6-SD, Tmsv6-Dif, Tmsv6-SD%, Tmsv6-Dif%: there were no significant differences between the two groups(P>0.05). Conclusions: RT－3DE can be used to access left ventricular volume and systolic function changes of late-stage cirrhosis and it is a convenient, practical method to evaluate left ventricular volume and systolic function.
2007, Vol. 18 
