Abstract：Objective: To investigate the diagnostic value of the histogram analysis derived from enhancement MR imaging in differentiating medulloblastomas from ependymoma. Methods and Materials: Retrospective analysis of pathologically confirmed 36 cases of posterior fossa tumors, including 20 cases of medulloblastoma, 16 cases of ependymoma, were performed. T1, T2 and enhanced T1 weighted magnetic resonance images were collected, tumor region of interest were extracted by the software of MaZda(region of interest, ROI), histogram analysis for the maximum level of tumor region of interest was undergone, the average value, variance, skewness, kurtosis, the 1, 10, 50, 90, 99 percentile characteristics were selected to find out the significant differences between the two kinds of tumors. Result: 9 texture parameters from histogram were with statistical significance(1 percent), and in the C1 ROC curve, the maximum area under ROC curve is 0.82, 46.5 as cut-off value specificity and sensitivity were 82% and 75%. Conclusion: Histogram analysis can provide more quantitative information characteristics, which provides a new method for the differential diagnosis of children with medulloblastoma and ependymoma.
汪卫建，程敬亮，张 勇，郭亚飞. 增强MRI直方图鉴别儿童后颅窝髓母细胞瘤和室管膜瘤的价值[J]. 中国临床医学影像杂志, 2018, 29(5): 305-308.
WANG Wei-jian, CHENG Jing-liang, ZHANG Yong, GUO Ya-fei. Enhancement of MRI histogram in the identification of children with medulloblastoma and ependymoma. JOURNAL OF CHINA MEDICAL IMAGING, 2018, 29(5): 305-308.
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2018, Vol. 29 
