Ultrasound-based scoring system for differential diagnosis of Warthin tumors and pleomorphic adenomas in parotid gland
HAN Ming-li1, WANG Dong-hua2, SHI Qiu-sheng1, CHEN Hong-yan2, ZHU Hui2, DU Lian-fang1
1. Department of Ultrasound, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200080, China;
2. Department of Ultrasound, Minhang Hospital, Fudan University, Shanghai 201199, China
Abstract:Objective: To evaluate the value of ultrasound-based scoring system in differential diagnosis of Warthin tumors and pleomorphic adenomas in parotid gland. Methods: Forty Warthin tumors and 41 pleomorphic adenomas were proved by surgical histopathology after the ultrasonography process. And the parameters including gender, age, maximum diameter, height/width ratio, number of lesions, echogenicity, reticular cord, shape, margin, posterior echogenicity, cystic degeneration, calcification and blood flow were retrospectively compared between the groups mentioned above. After that, the independent risk factors were screened by multivariate stepwise Logistic regression analysis. Then, a scoring system was established. The receiver operating characteristic(ROC) curve was also plotted to calculate the diagnostic efficacy of the scoring system. Results: There were statistically significant differences between the two groups in the next eight parameters including gender, age, maximum diameter, height/width ratio, number of lesions, echogenicity, reticular cord, and blood flow(P<0.05). Furthermore, among of which, the gender, age, height/width ratio, echogenicity, or blood flow was individually independent risk factors to Warthin tumors. The scoring system was established with 0 or 1 point for each risk factor, and the total scores summed up to 0~5 points. The highest efficiency, the sensitivity, specificity and accuracy of the diagnosis of Warthin tumors were 97.5%, 85.36% and 91.35% while the cut-off value of ≥3 was set, respectively. Conclusion: The ultrasound-based scoring system has highly diagnostic efficiency in differentiating Warthin tumors from pleomorphic adenomas in parotid gland. Though simple, but it is an easy way to perform in clinical practice.
韩明丽1,王栋华2,史秋生1,陈红燕2,朱 慧2,杜联芳1. 基于超声特征的评分法在腮腺Warthin瘤与混合瘤鉴别诊断中的应用研究[J]. 中国临床医学影像杂志, 2020, 31(6): 385-389.
HAN Ming-li1, WANG Dong-hua2, SHI Qiu-sheng1, CHEN Hong-yan2, ZHU Hui2, DU Lian-fang1. Ultrasound-based scoring system for differential diagnosis of Warthin tumors and pleomorphic adenomas in parotid gland. JOURNAL OF CHINA MEDICAL IMAGING, 2020, 31(6): 385-389.
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