Abstract：Objective: To investigate the value of combination of MRI histogram and dynamic enhanced TIC in the differential diagnosis of breast fibroadenoma and invasive ductal carcinoma. Methods: A retrospective analysis of 15 cases of breast fibroadenoma confirmed by surgery and pathology in our hospital and 32 cases of invasive ductal carcinoma were performed. All patients underwent breast MRI and dynamic contrast-enhanced scanning. We plotted the TIC and measure the histogram parameters of the lesion, including mean, variance, skewness, kurtosis, and 10th, 50th, 90th percentiles. The differences between breast fibroadenoma and invasive ductal carcinoma parameters were compared using the χ2 test and the independent sample t test using SPSS 22.0 statistical analysis software. Results: The TIC was statistically different between the two groups(P<0.05). The kurtosis values in the histogram parameters were statistically significant(P<0.01) in the third phase of dynamic contrast-enhanced scanning. The correlation analysis found that the mean and variance values were strongly positively correlated in the first, third phases of the enhanced scan and T2 sequence(P<0.01), the kurtosis value and the skewness value were strongly negatively correlated in each sequence(P<0.01). The combined diagnosis of the two methods can improve the sensitivity and specificity of breast invasive ductal carcinoma. Conclusion: The combined diagnosis of MRI histogram and dynamic enhanced TIC curve is useful for the differential diagnosis of breast fibroadenoma and invasive ductal carcinoma.
孟丽辉1，钱丽霞2，郭晓媛2. MRI直方图结合TIC曲线鉴别乳腺纤维腺瘤与浸润性导管癌的价值[J]. 中国临床医学影像杂志, 2019, 30(8): 544-547.
MENG Li-hui1, QIAN Li-xia2, GUO Xiao-yuan2. Value of MR histogram combined with TIC in differential diagnosis of breast fibroadenoma and invasive ductal carcinoma. JOURNAL OF CHINA MEDICAL IMAGING, 2019, 30(8): 544-547.
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