腰椎间盘突出症髓核摘除手术前后弥散张量成像参数变化的研究

崔婷婷1; 岳云龙1; 金延方1; 左利利1; 任  杰1; 李松柏2

doi:10.12117/jccmi.2020.06.015

中国临床医学影像杂志 ›› 2020, Vol. 31 ›› Issue (6) : 438-440. DOI: 10.12117/jccmi.2020.06.015

肌肉骨骼影像学

腰椎间盘突出症髓核摘除手术前后弥散张量成像参数变化的研究

崔婷婷1，岳云龙1，金延方1，左利利1，任杰1，李松柏2

作者信息 +

Study on changes in paraments of diffusion tensor imaging with lumbar disc herniation before and after discectomy

CUI Ting-ting1, YUE Yun-long1, JIN Yan-fang1, ZUO Li-li1, REN Jie1, LI Song-bai2

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文章历史 +

摘要

目的：探讨单一节段腰椎间盘突出症患者髓核摘除手术前后受压神经根弥散张量成像（DTI）相关参数（FA值和ADC值）变化及其与病程的相关性。方法：对25例接受经皮椎间孔镜髓核摘除术（PTED）的单一节段腰椎间盘突出症患者进行术前及术后3月两次DTI扫描，测量手术前后患侧及健侧神经根FA和ADC值；记录每位患者的病程并分析DTI相关参数和病程的相关性。结果：术前患侧神经根FA值较健侧减低（P=0.000）；术后患侧FA值较术前升高（P=0.000）、较健侧仍减低（P=0.038）。术后患侧ADC值低于术前（P=0.019），术前及术后患侧及健侧神经根ADC值均未见统计学差异（P＞0.05）。手术前后患侧神经根FA值的差值与病程呈显著负相关（r=-0.751，P=0.000）。结论：DTI可能是评价腰椎间盘突出症患者术后神经根微观结构改变的重要工具，对临床可能会具有指导意义。

Abstract

Objective: To investigate the changes of paraments of compressed nerve roots on diffusion tensor imaging(DTI) such as fractional anisotropy(FA) and apparent diffusion coefficient(ADC) in patients with single lumbar disc herniation before and after discectomy and the relationship between the paraments and the duration of symptoms. Methods: A total of 25 patients with percutaneous transforaminal endoscopic discectomy underwent DTI scanning before and three months after surgery. The FA and ADC values of the compressed and intact nerves were measured. Record the duration of symptoms and analyze the correlation between paraments and the duration. Results: The FA values of the compressed nerve roots were lower than intact nerves(P=0.000); The FA values increased at three months after surgical treatment(P=0.000), but they were still lower than intact nerves(P=0.038). The ADC values decreased at three months after surgical treatment(P=0.019), but no significant difference was found between the compressed and normal sides before and after surgery(P>0.05). There was a strong negative correlations between the difference of FA values of the compressed nerve roots before and after surgery and the duration of symptoms(r=-0.751, P=0.000). Conclusion: DTI may be an important tool to evaluate the structural changes of nerve roots in patients with lumbar disc herniation and that may has very important guiding significance in the clinical treatment.

导出引用

崔婷婷1，岳云龙1，金延方1，左利利1，任杰1，李松柏2. 腰椎间盘突出症髓核摘除手术前后弥散张量成像参数变化的研究[J]. 中国临床医学影像杂志. 2020, 31(6): 438-440 https://doi.org/10.12117/jccmi.2020.06.015

CUI Ting-ting1, YUE Yun-long1, JIN Yan-fang1, ZUO Li-li1, REN Jie1, LI Song-bai2. Study on changes in paraments of diffusion tensor imaging with lumbar disc herniation before and after discectomy[J]. Journal of China Clinic Medical Imaging. 2020, 31(6): 438-440 https://doi.org/10.12117/jccmi.2020.06.015

中图分类号： Ｒ681.53 Ｒ445.2

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