实时剪切波弹性成像在鉴别胆道闭锁和胆汁淤积的诊断价值

doi:10.12117/jccmi.2019.06.011

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Abstract Objective: To evaluate the accuracy of ultrasonic shear wave elastography in detecting biliary atresia and cholestasis in measuring the liver stiffness of infants. Methods: Color Doppler ultrasound diagnostic apparatus, SC6-1 convex array probe and SL10-2 linear array probe were used to switch to the SWE mode after selecting the appropriate incision in the right intercostal space of infants to avoid the large intrahepatic pipe structure, the elastic imaging sampling frame placed in the right lobe Ⅴ, Ⅵ subhepatic 0.5 cm within the liver parenchyma. Quantitative detection of Q-box diameter of 15~20 mm circular area was selected in the imaging area to display and record the mean of liver elastic modulus in the detection area. Each of the infants was tested 5 times at the same site, and the mean was taken. The ANOVA was used to compare the liver stiffness values of biliary atresia group, infant hepatitis group and control group. Receiver operating characteristic curve(ROC curve) was used to determine the diagnostic boundary value between the liver stiffness value of biliary atresia and infantile cholestasis. Results: The liver stiffness values of SC6-1 probe detection of biliary atresia, infantile cholestasis and normal control infant liver stiffness values were (15.8±8.9) kPa, (8.4±2.1) kPa, (4.9±0.6) kPa. The liver stiffness values of SL10-2 probe detection of biliary atresia, cholestasis and normal control infants were (13.5±7.7) kPa, (7.5±1.9) kPa, (4.4±0.6) kPa. When the liver stiffness detected by the SC6-1 probe was 8.85 kPa, the ROC curve diagnostic sensitivity and specificity of identifying the biliary atresia and cholestasis were 100% and 75% respectively. When the liver stiffness detected by the SL10-2 probe was 7.60 kPa, the ROC curve diagnostic sensitivity and specificity of identifying the biliary atresia and cholestasis were 92% and 75% respectively. Conclusion: Real-time shear wave elastography can effectively identify infants with biliary atresia and infantile cholestasis.

Key words： Biliary atresia Cholestasis Ultrasonography, Doppler, color

Received: 17 July 2018

PACS:	Ｒ575.7
	Ｒ445.1

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	Articles by authors
	LIU Qin
	SU Ying-zi
	REN Hong-yan
	ZHANG Wei-wei
	MA Ya
	WANG Zheng-rong

Cite this article:

LIU Qin,SU Ying-zi,REN Hong-yan, et al. Application value of real-time shear wave elastography in diagnosis of biliary atresia and cholestasis[J]. JOURNAL OF CHINA MEDICAL IMAGING, 2019, 30(6): 421-424.

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http://www.jccmi.com.cn/EN/10.12117/jccmi.2019.06.011 OR http://www.jccmi.com.cn/EN/Y2019/V30/I6/421

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