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The application of VTI and VTIQ in differential diagnosis of small solid mammary nodules |
LIU Jie, WANG Rong, WANG Xing-tian, SHA Yu-meng, HUANG Rui, WANG Yu-qiao |
Department of Ultrasound, the Affiliated Hospital of Xuzhou Medical University, Xuzhou Jiangsu 221006, China |
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Abstract Objective: To evaluate the application value of virtual touch tissue imaging(VTI) and virtual touch tissue imaging quantification(VTIQ) in differential diagnosis of small solid mammary nodules(diameter ≤10 mm). Methods: A total of 52 patients with 60 small solid mammary nodules from Breast Surgery Department in our hospital all underwent the routine ultrasound examination firstly, and the nodules were classified by BI-RADS. Then the VTI and VTIQ examinations were performed. The hardness scores of nodules were obtained by VTI. The shear wave velocity(SWV) values of nodules were obtained by VTIQ. The ROC curve was drawn to obtain the cut-off value of the small solid mammary nodules by VTIQ by using pathological diagnosis as the gold standard. The diagnostic value of BI-RADS classification, VTI and VTIQ for the benign and malignant small solid mammary nodules was evaluated. Results: The proportion of malignant group of the small solid mammary nodules(16/18) whose VTI hardness score ≥4 was significantly higher than that of the benign group(11/42). The mean SWV of the malignant group (6.37±1.96) m/s was significantly higher than that of the benign group (3.38±1.27) m/s. The difference was statistically significant(P<0.05). The cut-off value of SWV by VTIQ was 4.58 m/s for the diagnosis of small solid mammary nodules. The area under the ROC curve of BI-RADS classification, VTI and VTIQ was 0.720, 0.860, 0.924, respectively. The difference between every two group was statistically significant(P<0.05). Conclusions: VTI and VTIQ conduce to evaluate and differentiate small solid mammary nodules. VTIQ has more important clinical application value in judging the benignity and malignity of small solid mammary nodules.
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Received: 10 August 2018
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