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| The value of prenatal diagnosis of fetal malformation of cortical development by MRI |
| KANG Min, TAO Yuan-ping, WANG Shi-qi, ZOU Xue-jin, DING Li |
| Department of Radiology, Sichuan Women and Children Health Care Hospital, Chengdu 610041, China |
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Abstract Objective: Summarizing the MRI features of fetal cerebral cortex development malformation(MCD) to improve the ability of diagnosis and differential diagnosis. Methods: Retrospectively analyzing the MRI findings of 21 patients with MCD, and summarizing the relationship of the features of MRI and gestational age. Results: Twenty-one abnormal fetuses: 2 cases of hemimegyria, 3 cases of paraventricular nodular ectopia of gray matter(PNH), 6 cases of anencephaly, 2 cases of congenital muscular dystrophy(CMD), 2 cases of polymicrogyria(PMG), 5 cases of schizencephaly, and 1 case of primary microcephary. Conclusion: MRI is the best imaging method to diagnose fetal MCD. Schizencephaly, CMD and hemimegyria can often be diagnosed in the second-trimester; anencephaly, PMG, PNH and microcephalusare more likely to be diagnosed in the third-trimester or postpartum, and confirmed by follow-up MRI.
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Received: 13 February 2019
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