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Predictive value of GSMPI phase analysis in development of heart failure in patients with left ventricular systolic dysfunction after AMI |
XU Xian-hai, GUO Xiao-shan, WU Zhi-fang, JIN Chun-rong, LI Li, WANG Ruo-nan, LI Si-jin |
First Hospital of Shanxi Medical University, Taiyuan 030001, China |
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Abstract Objective: To evaluate the predictive value of phase analysis of 99mTc-MIBI gated SPECT myocardial perfusion imaging(GSMPI) in patients with left ventricular systolic dysfunction(LVSD) after acute myocardial infarction(AMI) with post-revascularization. Methods: We retrospectively analyzed phase parameters of 100 patients with LVSD after AMI who underwent GSMPI and left ventricular ejection fraction(LVEF)≤40%, including phase histogram bandwidth(PHB) and phase standard deviation(PSD). The patients were divided into group with heart failure(group a) and group without heart failure(group b) according to follow-up results. The relevant parameters were compared between groups. ROC curve was used to evaluate optimal cutoff of PHB and PSD for predicting heart failure. Logistic regression model was used to evaluate independent predictors of heart failure. Results: End diastolic volume(EDV), end systolic volume(ESV), LVEF, summed rest score(SRS), total perfusion deficit(TPD), PHB and PSD showed significant difference between two groups. Optimal cutoffs of PHB and PSD were 87 and 25.9. PHB>87 was an independent predictor according to Logistic regression model. Conclusion: PHB of phase analysis was independent factor for predicting heart failure in patients of LVSD after AMI with post-revascularization.
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Received: 20 November 2018
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