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| The conservative therapy of heart failure improves pulmonary hypertension in dilated cardiomyopathy with the evaluation of echocardiographic strain imaging |
| LI Pu-nan, ZHANG Xiao-li, ZHAO Jia, SHEN Xi-ling, TIAN Kun, LI Qing-feng |
| Department of Ultrasound, Jincheng People’s Hospital, Jincheng Shanxi 048000, China |
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Abstract Objective: The aim of the study was to investigate the effect of conservative therapy on pulmonary hypertension(PH) and right ventricular(RV) function in DCM. Methods: This is a retrospective analysis of 60 consecutive DCM patients with evaluation of echocardiographic pulmonary artery systolic pressure(PASP) and right ventricular strain. Results: Compared with patients without PH, patients with PH(PASP≥35 mmHg) had worse left systolic and diastolic function. The ejection fraction increased post-therapy(P=0.046). Reduction of PASP post-therapy was evident in patients with PH(P＜0.001). The tricuspid annular plane systolic excursion(TAPSE) showed no significant difference post-therapy(P=0.102), however, the increase of the RV free wall strain was demonstrated post-therapy with strain imaging(P＜0.001). Compared with TAPSE, the correlation between RV free wall strain and right ventricular ejection fraction(magnetic resonance imaging) was better(r=0.808, P=0.008). Conclusion: The results of this study support the potential of strain imaging to estimate RV function, and adding significant value to conventional echocardiographic measurements.
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Received: 23 September 2019
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2020, Vol. 31 
