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The clinical and surgical application of DTI multiple parameter value and DTT in astrocytomas |
SUN Xi-lin, WANG Dan, SHEN Bao-zhong, LI Lin, HE Qi-wei, LIU Fang |
The Fourth Affiliated Hospital of Harbin Medical University, Harbin 150000, China |
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Abstract Objective: To investigate the clinical usefulness of DTI multiple parameter and diffusion tenser tracting(DTT) in astrocytomas. Methods: Thirty-three cases of astrocytomas underwent routine MRI, enhanced scanning and DTI before and/or after operation. DCavg, FA, 1-VR and RA values were measured in the solid part of tumors, the necrotic area, the peritumoral edema, the white matter area surrounding the edema and corresponding normal brain; and the white matter surrounding tumors were rebuilt with DTT. Results: The white matter of brain could be seen better in FA and DTI graph, and not in routine MRI. There was significant difference of ADC, DCavg, FA, 1-VR and RA values in the solid part of tumors, the necrotic area, the peritumoral edema and the white matter area surrounding the edema. The peritumoral white matter of most low-grade astrocytoma cases were displaced, while of high-grade astrocytomas were destroyed. Conclusion: Combined with conventional MR imaging, DCavg, FA, 1-VR and RA values were conduced to distinguish the solid part of tumors, the necrotic area, the peritumoral edema and the white matter area surrounding the edema in distinguishing astrocytoma grade; FA, 1-VR, and RA value were conduced to detect low-grade and high-grade astrocytomas. DTI and DTT can be used to select the better operation methods and evaluate effect of operation.
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Received: 08 January 2009
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