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| High frequency color Doppler ultrasonography in the diagnosis of ductal carcinoma in situ |
JIN Zhan-qiang, XU Xiao-hong
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| Department of Ultrasound, Affiliated Hospital of Guangdong Medical College, Zhanjiang Guangdong 524001, China |
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Abstract Objective: To evaluate the diagnostic value of high frequency ultrasonography(HFUS) through summarizing the ultrasonic signs of ductal carcinoma in situ(DCIS). Methods: The ultrasonographic features in 40 cases of DCIS proved by post-operative pathology and 30 cases of hyperplastic disease of breast(HDB) including boundary, internal echogenicity, microcalcification, posterior echogenicity, peak systolic velocity(PSV), resistance index(RI) and blood distribution, were analyzed. Results: The ultrasonographic features of DCIS are mass-forming type, patchy hypoechoic type, duct dilatation type and microcalcification type, accounted for 57.50%(23/40), 27.50%(11/40), 10.00%(4/40) and 5.00%(2/40), respectively. There are 7 patients with microinvasion, including 1 patient with axillary lymph node metastasis. Thirty-one cases of DCIS and 24 cases of HDB were diagnosed correctly by preoperative ultrasonography, the accuracy, specificity and sensitivity were 78.57%, 80.00% and 77.50% respectively. The positive predictive value and negative predictive value were 83.78% and 72.73% respectively. Microcalcification and RI were statistically significant(P<0.05) in differential diagnosis between DCIS and HDB. Conclusion: The ultrasonic characteristics of DCIS has certain specific features, HFUS diagnosis for DCIS are of great value.
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Received: 22 February 2011
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Corresponding Authors:
XU Xiao-hong
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2011, Vol. 22 
