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| The diagnostic value of fluid-fluid levels in distinguishing between benign and malignant bone lesions using CT/MR |
| CHENG Xiao-guang, SU Yong-bin, XU Li |
| Department of Radiology, Beijing Jishuitan Hospital, Beijing 100035, China |
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Abstract Objective: To analyze the diagnostic value of fluid-fluid levels in distinguishing benign and malignant bone lesions using CT/MR. Methods: Sixty-six cases of primary bone lesions proven by pathology were reviewed, among which 12 cases were examined by CT, 51 cases were examined by CT and MR, and the other 3 cases were examined by MR. Fluid-fluid levels(FFLs) were identified in all of the cases. The proportion of the lesion occupied by FFLs was estimated as <1/3, 1/3～<2/3, 2/3～<100% and 100%. The proportion was correlated with the pathological diagnosis and confirmed by double blind method. Results: Pathology revealed 58 benign bone lesions and 8 malignant bone lesions. When the degree of FFLs was <1/3, malignant lesions were relatively common(3/8, 37.5%), and all of which were osteosarcoma. With the increasing of FFLs degree, benign lesion became more frequent. When the degree was >2/3, 93.6% of lesions were benign, most of which were giant cell tumors with aneurysmal bone cysts or primary aneurysmal bone cysts. When the lesions were entire FFls, all of them were benign. Conclusions: More proportion of FFLs in primary bone lesion suggests more possibility of benign bone tumor.
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Received: 17 February 2012
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2012, Vol. 23 
