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| Coronary artery angiography with individualized low radiation dose in diagnosing ofcoronary heart disease: comparative analysis between CTA and DSA |
WANG Gang, ZHANG Zhen-tao, ZHENG Xiao-lin, ZHANG Yu-lan, CAI Qing-wen,
LIANG Man-qiu, YUAN Huan-chu, LI De-wei, CHEN Shao-ting, DENG Lei |
| Radiology Department of Dongguan People’s Hospital, Dongguan Guangdong 523000, China |
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Abstract Objective: To investigate the feasibility of individualized low radiation dose scanning of 256-slice CT in coronary artery imaging. Compared with DSA coronary angiography, to study the value of CTA in the diagnosis of coronary heart disease. Methods: 156 patients were divided into 4 groups: 78 cases in group A were prospectively ECG-gated scan, heart rate <80 bpm, including 36 cases of coronary DSA angiography; 78 cases in group B were retrospectively ECG-gated scan, including 60 cases of coronary DSA angiography. According to BMI, 78 cases in group B were divided into 3 groups: 25 cases in group B1(BMI<18 kg/m2), 25 cases in group B2(BMI 18~25 kg/m2), 28 cases in group B3(BMI>25 kg/m2). To scan with Philips 256-slice iCT of 120 kV and tube current with 992 mA in group A, 500 mA in group B1, 580 mA in group B2, 660 mA in group B3. Calculating the effective radiation dose(ED) after the scan. To evaluate image quality with subjective score(4 points) and objective measure of noise(SD). To analyse the differences of heart rate, ED, noise and image score between the two groups with SPSS 13.0 software. Results: Between group A and group B, there were statistically significant differences in heart rate and ED(P<0.05), that the mean difference of ED was 7.45 mSv between the two groups. Compared with group B, the mean ED in group A decreased by 50.41%. Differences between the two groups of BMI, the image SD and score had no statistically significance(P>0.05). Among group B1, B2, B3, the difference of image quality score and heart rate had no statistical significance. The difference of ED among the three groups had statistical significance. There was significant difference of noise between group B1 and B2, group B1 and B3, but no significant difference of noise between group B2 and B3. Compared with DSA, the sensitivity, specificity and accuracy in diagnosing coronary heart disease in group A was 91.19%, 95.64%. Conclusion: In the coronary artery CTA examination, it may be effectively reduced the individual radiation dose in the premise of ensuring the diagnosis accuracy and image quality, with classification of patients by heart rate, BMI, tube current and so on.
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Received: 13 March 2014
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Corresponding Authors:
ZHENG Xiao-lin
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2014, Vol. 25 
