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| The clinical application value of molecular imaging SPECT/CT for bone metastases from breast cancer |
| DONG Ke, FU Jian-fei, LOU Jing-jing, LIU Jiang |
| Department of Nuclear Medicine, Jinhua Central Hospital, Jinhua Zhejiang 321000, China |
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Abstract Objective: To investigate the clinical application value of the molecular imaging SPECT/CT for bone metastases of breast cancer. Methods: Both MSCT and SPECT/CT imaging data of 68 suspicious bone metastases lesions of breast cancer were retrospectively analyzed and compared, and the statistics checkout was carried out. Resluts: Among the 55 bone metastases lesions of breast cancer, sensitivity, specificity and accuracy of bone metastases diagnosed by MSCT were 78.2％(43/55), 92.3%(12/13) and 80.9%(55/68); and sensitivity, specificity and accuracy of bone metastases diagnosed by SPECT/CT were 96.4％(53/55), 76.9%(10/13) and 92.6%(63/68). For the difference of the sensitivity and accuracy, there was statistically significance between MSCT and SPECT methods(P＜0.05), and the specificity of both methods was no difference. Conclusions: Comparing with MSCT, the SPECT/CT fusion imaging can improve the sensitivity and accuracy of the bone metastases diagnosis of breast cancer, and having better clinical application value.
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Received: 16 December 2014
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Corresponding Authors:
FU Jian-fei
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2015, Vol. 26 
