儿童骶尾部卵黄囊瘤的影像学表现

Abstract
Figure/Table
References (0)
Related Citation (15)

Download: PDF (0 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective: To improve the accuracy of preoperative diagnosis of sacrococcygeal yolk sac tumor in children by correlating the CT or MR imaging features with histopathology. Methods: CT or MR imaging findings of sacrococcygeal yolk sac tumor in 21 cases confirmed by surgery and pathology were retrospectively reviewed. Results: All the 21 tumors appeared as soft-tissue masses and most of them were well-defined. The tumors were heterogeneous in terms of density or signal intensity and were always associated with different degree of necrotic and cystic change area. Among them, 7 cases showed blood vessels enhancement on contrast-enhanced CT or MRI, 6 cases showed small patch intratumor hemorrhage. All the 21 cases surrounded and invaded the coccyx, with 7 cases extending into the canalis vertebralis. What is more, multiple lung metastases were found in 9 cases and bone metastases were shown in 2 cases. All the 12 cases demonstrated hetergeneous hyperintensity on DWI, with the ADC value was between (0.63~1.32)×10-3 mm2/s. Serum AFP level of all the 21 yolk sac tumors increased. Conclusion: Sacrococcygeal yolk sac tumors always occurs in infants and young children, especially less than 3 years old, and are prone to hemorrhage, necrosis and cystic change. CT or MRI examination combined with serum AFP examination can improve the accuracy of preoperative diagnosis, and also can determine the range of tumor involvement, which is important for selection for clinical treatment and prognosis assessment.

Key words： Endodermal sinus tumor Sacrococcygeal region Child Tomography, X-ray computed Magnetic resonance imaging

Received: 11 August 2015

PACS:	Ｒ738.1
	R445.2
	Ｒ814.42

Corresponding Authors: WANG Deng-bin

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	LU Zheng-hai
	DING Ming
	CAI Jing
	CUI Xue-e
	ZHU Jing-yu
	ZHU Jin-yong
	WANG Deng-bin

Cite this article:

LU Zheng-hai,DING Ming,CAI Jing, et al. Imaging findings of sacrococcygeal yolk sac tumor in children[J]. JOURNAL OF CHINA MEDICAL IMAGING, 2016, 27(3): 198-201.

URL:

http://www.jccmi.com.cn/EN/ OR http://www.jccmi.com.cn/EN/Y2016/V27/I3/198

[1]Kocaoglu M, Frush DP. Pediatric presacral masses[J]. Radiographics, 2006, 26(3): 833-857.
[2]Calaminus G, Schneider DT, Bokkerink JP, et al. Prognostic value of tumor size, metastases, extension into bone, and increased tumor marker in children with malignant sacrococcygeal germ cell tumors: a prospective evaluation of 71 patients treated in the German cooperative protocols Maligne Keimzell tumor en(MAKEI) 83/86 and MAKEI 89[J]. J Clin Oncol, 2003, 21(5): 781-786.
[3]Marina N, London WB, Frazier AL, et al. Prognostic factors in children with extragonadal malignant germ cell tumors: a pediatric intergroup study[J]. J Clin Oncol, 2006, 24(16): 2544-2548.
[4]Baranzelli MC, Kramar A, Bouffet E, et al. Prognostic factors in children with localized malignant nonseminomatous germ cell tumors[J]. J Clin Oncol, 1999, 17(4): 1212.
[5]Steinbacher DM, Upton J, Rahbar R, et al. Yolk sac tumor of the mandible[J]. J Oral Maxillofac Surg, 2008, 66(1): 151-153.
[6]Altman RP, Randolph JG, Lilly JR. Sacrococcygeal teratoma: American Academy of Pediatrics Surgical Section Survey-1973[J]. J Pediatr Surg, 1974, 9(3): 389-398.
[7]Rescorla FJ. Pediatric germ cell tumors[J]. Semin Pediatr Surg, 2012, 21(1): 51-60.
[8]Horton Z, Schlatter M, Schultz S. Pediatric germ cell tumors[J]. Surg Oncol, 2007, 16(3): 205-213.
[9]Ueno T, Tanaka YO, Nagata M, et al. Spectrum of germ cell tumors: from head to toe[J]. Radiographics, 2004, 24(2): 387-404.
[10]Yoshida M, Matsuoka K, Nakazawa A, et al. Sacrococcygeal yolk sac tumor developing after teratoma: a clinicopathological study of pediatric sacrococcygeal germ cell tumors and a proposal of the pathogenesis of sacrococcygeal yolk sac tumors[J]. J Pediatr Surg, 2013, 48(4): 776-781.
[11]Sayed HA, Ali AM, Hamza HM, et al. Sacrococcygeal tumors: clinical characteristics and outcome of pediatric patients treated at South Egypt Cancer Institute. A retrospective analysis[J]. J Pediatr Surg, 2013, 48(7): 1604-1608.
[12]Lo Curto M, D’Angelo P, Cecchetto G, et al. Mature and immature teratomas: results of the first pediatric Italian study[J]. Pediatr Surg Int, 2007, 23(4): 315-322.
[13]De Backer A, Madern GC, Hakvoort-Cammel FG, et al. Study of the factors associated with recurrence in children with sacrococcygeal teratoma[J]. J Pediatr Surg, 2006, 41(1): 173-181.
[14]International Germ Cell Cancer Collaborative Group. International Germ Cell Consensus Classification: a prognostic factor-based staging system for metastatic germ cell cancers[J]. J Clin Oncol, 1997, 15(2): 594-603.
[15]许恪淳，管雯斌，许艳春，等. 儿童卵黄囊瘤病理学特征及鉴别诊断[J]. 上海交通大学学报：医学版，2013，33（2）：200-203.
[16]翟健坤，粱欢庆．盆部内胚窦瘤临床表现及CT特征[J]．实用医学影像杂志，2009，10（2）：116-118.
[17]李文华，张永平，俞炬明. 小儿骶尾部生殖细胞源性肿瘤的CT诊断和MRI诊断[J]. 中国医学计算机成像杂志，2001，7（6）：406-408．
[18]范森，彭谦，王晓燕．小儿骶前肿瘤的CT诊断和MRI诊断[J]. 癌症，2009，28（4）：420-424．
[19]Choi HJ, Moon MH, Kim SH, et al. Yolk sac tumor of the ovary: CT findings[J]. Abdom Imaging, 2008, 33(6): 736-739.
[20]Yamaoko T, Togashi K, Koyamo T, et al. Yolk sac tumor of the ovary: radiologic-pathologic correlation in four cases[J]． J Comput Assist Tomogr, 2000, 24(4): 605-609．
[21]Li Y, Zheng Y, Lin J, et al. Radiological-pathological correlation of yolk sac tumor in 20 patients[J]. Acta Radiol, 2016, 57(1): 98-106.
[22]Amzallag-Bellenger E, Soyer P, Barbe C, et al. Diffusion-weighted imaging for the detection of mesenteric small bowel tumours with magnetic resonance enterography[J]. Eur Radiol, 2014, 24(11): 2916-2926.