2型糖尿病患者脑部小血管病变的MRI评价

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Abstract Objective: To evaluate the manifestation of cerebral small vessel damage of type 2 diabetes using noninvasive techniques of MR imaging, and to provide useful information for clinical diagnosis, therapy, and long term evaluation of diabetes. Materials and Methods: Four hundred and thirty-seven neurology inpatients were recruited in our study between January 2013 and December 2013, eighteen cases were excluded. Diabetes group and non-diabetes group were observed. All patients underwent brain MRI with T1WI, T2WI, FLAIR, DWI, SWI and T2WI sequences in 3.0T scanner. The incidence rate and distribution pattern of acute infarction, cerebral micro hemorrhage, the number of lacunar infarction and the degree of leukoaraiosis were recorded. Results: The incidence rate of infarction caused by small vessel occlusion was higher in diabetes group than in non-diabetes group(68.2% vs 43.2%). There was statistical difference between diabetes group and non-diabetes group(χ2=7.49, P<0.05). Compared with non-diabetes, diabetes group showed up more serious degree in previous cerebral apoplexy, lacunar infarction and leukoaraiosis. There was no statistical difference in the occurrence rate of cerebral micro-hemorrhage between the two groups(P>0.05). Conclusion: Small lesions was mainly presented in acute infarction happened in patients with type 2 diabetes. The severity of lacunar infarction and leukoaraiosis occurred in diabetes group was severer than that in non-diabetes group.

Key words： Diabetes mellitus, type 2 Diabetic angiopathies Cerebrovascular disorders Magnetic resonance imaging

Received: 21 October 2015

PACS:	Ｒ643
	Ｒ445.2

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	Articles by authors
	XIAO Zheng-guang
	YANG Jun
	ZHU Cai-song
	SHAO Kang-wei
	YUAN Li-xin
	MIN Qing-hua
	GU Feng
	LU Wen-jie

Cite this article:

XIAO Zheng-guang,YANG Jun,ZHU Cai-song, et al. MRI features of cerebral small vessel disease in patients with type 2 diabetes mellitus[J]. JOURNAL OF CHINA MEDICAL IMAGING, 2016, 27(5): 318-322.

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http://www.jccmi.com.cn/EN/ OR http://www.jccmi.com.cn/EN/Y2016/V27/I5/318

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