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| Preliminary research on the elastic changes in the liver of biliary atresia measured by#br# ultrasonic real time shear wave elasticity |
| Department of Ultrasound, Shengjing Hospital of China Medical University, Shenyang 110004, China |
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Abstract Objective: To investigate the elastic changes of liver in children with biliary atresia(BA) with ultrasonic real time shear wave elasticity(SWE). Method: Twenty-five cases of children with BA, 30 cases of infantile hepatitis syndrome(IHS) and 23 cases of infants with normal liver function were examined with SWE. The liver stiffness by Young’s modulus value was measured from the liver tissue locating about 2 cm from the liver border, and then compared among different groups. Result: The Young’s modulus values of BA group, IHS group and the normal group were (18.10±10.70) kPa, (6.68±1.98) kPa and (5.69±0.70) kPa, respectively, with a significant difference among the group(P<0.05). The Young’s modulus values were significantly different between group BA and IHS, and between group HIS and normal group. The Young’s modulus value in group BA showed a positive linear relationship with the age. Conclusion: SWE may assess liver fibrosis in children with BA indirectly, and can provide information of liver stiffness for the diagnosis of biliary atresia. It can also provide important evidence for clinicians to select the operation time and determine prognosis of biliary atresia in children.
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Received: 23 November 2015
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Corresponding Authors:
LI Shi-xing
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