CT与核素骨显像诊断SAPHO综合征的对比分析

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Abstract Objective: To explore the CT and bone scintigraphy features of patients with synovitis, acne, pustulosis, hyperostosis and osteitis(SAPHO) syndrome. Methods: CT and 99mTc-MDP features of 29 cases with SAPHO syndrome were retrospectively analyzed. Results: Twenty-four patients had anterior chest wall involved on CT, which showed bone sclerosis, hyperostosis, costal cartilage sclerotic hyperostosis, joint destruction and ankylosis; ten patients also had sacroiliac joint involvement, which showed sclerosis and hyperostosis on the iliac side of the sacroiliac joint, destruction of the articular surface and narrowing of joint space; eight patients had spinal involvement, which showed end plate erosion, sclerosis, paravertebral ossification, narrowed disc space, wedged body. Bone scintigraphy showed an increased uptake in ostearticular involvement. The anterior chest wall involvement was the commonest; it was presented in 27 patients(93.1%). Symmetric uptake in the sternoclavicular region with a typical “bull-horn” appearance was shown in bone scintigraphy by characteristic of the SAPHO syndrome. The uptake was also localized in: sacroiliac joints in 11, spine in 8, mandible, thighbone-one in each patient. Conclusion: Multi-bones of anterior chest wall involved was the common imaging characteristics, CT can accurately demonstrate bone sclerosis, hyperostosis, destruction and joint ankylosis. Bone scintigraphy can be very useful for an early diagnosis and localize the insidious lesion. SAPHO syndrome should be considered as they had the anterior chest wall involved and typical radiological features.

Key words： Acquired hyperostosis syndrome Tomography, spiral computed Tomography, emission-computed, single-photon

Received: 28 October 2015

PACS:	Ｒ681
	Ｒ814.42
	Ｒ817.4

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	Articles by authors
	ZHANG Qiang
	CIDAN Wang-jiu
	SUN Hong-zan
	GUO Qi-yong

Cite this article:

ZHANG Qiang,CIDAN Wang-jiu,SUN Hong-zan, et al. Comparison analysis of CT and bone scintigraphy in diagnosis of SAPHO syndrome[J]. JOURNAL OF CHINA MEDICAL IMAGING, 2016, 27(8): 589-593.

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http://www.jccmi.com.cn/EN/ OR http://www.jccmi.com.cn/EN/Y2016/V27/I8/589

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