CT引导下125I粒子植入治疗恶性肿瘤的临床研究

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Abstract Objective: To investigate the feasibility, clinical efficacy and influencing factors of 125I particles in the treatment of malignant tumors. Methods: The clinical data of 38 patients with malignant tumors treated by CT-guided 125I seed therapy in our hospital from April 2013 to March 2016 were retrospectively analyzed. The preoperative and postoperative tumor volume changes of 2 months and 6 months were compared. According to the changes of tumor volume, blood supply or tumor metabolic changes, the curative effect was graded(CR: complete remission, PR: partial remission, SD: tumor stability, PD: progression of disease, CR+PR for the total effective rate), and its short-term curative effect was evaluated. The data were analyzed by SPSS 17.0 statistical software before and after operation. The t test was used for statistical analysis. The difference of P<0.05 was statistically significant. Results: Postoperative 2 months, CR: 3 cases, PR: 18 cases, SD: 15 cases, PD: 2 cases, CR+PR: 55.26%; 6 months after operation, CR: 6 cases, PR: 21 cases, SD: 9 cases, PD: 2 cases; CR+PR: 71.05%. There was a significant difference in tumor volume at preoperative and postoperative 2 and 6 months(P<0.05). Conclusion: 125I seed implantation is a safe and effective method for the treatment of malignant tumor with less trauma, less adverse reaction, and satisfactory clinical efficacy in the control of tumor growth and the clinical symptoms of patients.

Key words： Neoplasms, second primary Iodine Tomography, X-ray computed

Received: 26 July 2016

PACS:	Ｒ73
	Ｒ814.42
	Ｒ815

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	Articles by authors
	CHEN Zhong-qian
	TIAN Feng
	HE Guang-shun
	ZHAO Xiao-peng
	ZHOU Dong-hai

Cite this article:

CHEN Zhong-qian,TIAN Feng,HE Guang-shun, et al. Clinical research of CT-guided 125I seed implantation in the treatment of malignant tumor[J]. JOURNAL OF CHINA MEDICAL IMAGING, 2017, 28(4): 282-284.

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http://www.jccmi.com.cn/EN/ OR http://www.jccmi.com.cn/EN/Y2017/V28/I4/282

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