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| Diagnostic value of dynamic volume CT in vertebrobasilar dolichoectasia syndrome |
| Department of Radiology, Wuhan General Hospital of PLA, Wuhan 430070, China |
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Abstract Objective: To evaluate value of dynamic volume CT(DVCT) using “a one-stop protocol for stroke” in the diagnosis of vertebrobasilar dolichoectasia(VBD). Methods: Twenty two patients(male/female=16/6, aged 39~79 years old) with DVCT-confirmed VBD were included into this study. For each patient with VBD, the location score and height score of basilar artery(BA) were determined and the BA diameter were measured in a post-processing workstation, as well perfusion status of the posterior circulation area were evaluated using a whole-brain perfusion analysis software. Results: Of 22 patients, the BA diameter was (6.12±1.73) mm on average(range 3.9~10.1 mm), the averaged BA height and location score were 2.32±0.48 and 2.32±0.78(range 1 to 3) respectively. Posterior-circulation abnormal perfusion were detected in 11 patients with VBD(50%), which was characterized by inordinately increased TTP, and increased rCBF and contracted MTT and presence of brain infarct lesions in serious cases. Between normal perfusion in posterior-circulation area and abnormal perfusion groups, there have significant difference both the BA position score and BA diameter(Mann-Whitney U test, P<0.05). Conclusion: For patients with VBD, DVCT examination could well demonstrate the morphologic abnormality in vertebrobasilar arteries and abnormal perfusion in posterior circulation.
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Received: 12 December 2016
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[1]Smoker WR, Corbett JJ, Gentry LR, et al. High-resolution computed tomography of the basilar artery: 2. Vertebrobasilar dolichoectasia: clinical-pathologic correlation and review[J]. AJNR, 1986, 7(1): 61-72.
[2]Yuan YJ, Xu K, Luo Q, et al. Research progress on vertibrobasilar dolichoectasia[J]. Int J Med Sci, 2014, 11(10): 1039-1048.
[3]Forster A, Kerl HU, Wenz H, et al. Fluid Attenuated Inversion Recovery Vascular Hyperintensities Possibly Indicate Slow Arterial Blood Flow in Vertebrobasilar Dolichoectasia[J]. J Neuroimaging, 2015, 25(4): 608-613.
[4]刘忠，王丽，陈信坚，等. 320排动态容积CT诊断脑血管病的价值[J]. 中国临床神经外科杂志，2013，18（7）：391-393.
[5]Ubogu EE, Zaldat OO. Vertebrobasilar dolichoectasia diagnosed by magnetic resonance angiography and risk of stroke and death: a cohort study[J]. J Neurol Neurosttrg Psychiatry, 2004, 75(4): 22-26．
[6]Gutierrez J． Dolichoectasia and risks of stroke and vascular disease: a critical appraisal[J]. Curr Cardiol Rep, 2014, 16(9): 525.
[7]王淑敏，孙丽丽，焦景松，等. 椎基底动脉延长扩张症患者并发脑梗塞的相关危险因素[J]. 神经疾病与精神卫生，2014，14（6）：620-623.
[8]张丽，万慧，韩国哲，等. 缺血性卒中患者椎基底动脉扩张延长症的临床和影像学特征：回顾性病例系列研究[J]. 国际脑血管病杂志，2012，20（9）：672-677. |
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