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| Evaluation of 3D ASL imaging in mild traumatic brain injury |
| XIE Xiu-hai1, TANG Guang-yu1， ZHAO Zhen-guo2, QIAN Bang-wei2, SUI Hai-jing2, YANG Liu-qing2, YANG Wen-jing2 |
1. Department of Radiology, Shanghai Tenth People’s Hospital, Tongji University, Shanghai 200072, China;
2. Shanghai Pudong New Area People’s Hospital, Shanghai 201200, China |
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Abstract Objective: To evaluate the diagnostic and prognostic value of three-dimensional arterial spin labeling(3D ASL) in patients with the mild traumatic brain injury(mTBI). Methods: Thirty-five mTBI patients with negative CT and 25 healthy volunteers underwent conventional MRI and 3D ASL examination. After 3 months of brain trauma, the RPQ score of the patients group was used as a prognostic indicator. Results: Of the 35 patients with mTBI, regional hypoperfusion was found in 17 cases. Thirteen cases(RPQ score>14) were positive for post concussion syndrome(PCS). Of the 17 patients with rCBF local hypoperfusion, 11(64.70%) were positive for PCS, and 18 had no significant local hypoperfusion, and only 2(11.11%) were positive for PCS. In patients with mTBI, the probability of PCS in the local hypoperfusion group was significantly higher than that in the non local hypoperfusion group(P<0.01). Conclusion: 3D ASL perfusion imaging can quantitatively detect the decrease of cerebral blood flow in patients with mTBI. It is of great significance to detect and correct the abnormal brain microcirculation and improve the prognosis of the patients.
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Received: 13 October 2017
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