彩色超微血管成像技术对活动期类风湿关节炎的评估

doi:DOI:10.12117/jccmi.2018.12.014

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Abstract Objective: To explore the application of color superb microvascular imaging(cSMI) in evaluating the rheumatoid arthritis(RA) in the active period. Methods: Sixty-two patients with RA in the active period were collected. Ultrasound was used to examine the wrist(Wri) joints and metacarpophalangeal(MCP) joints and proximal interphalangeal(PIP) joints of each patient’s bilateral hands. The numbers of thickened synovial joints were recorded. Blood flow signal of the thickened synovial joints was checked by the cSMI and power doppler ultrasound(PDUS) separately. Color flow signal was graded by the semi-quantitative scoring systems. The correlations between the blood flow signal score of PDUS and cSMI and 28 joint disease activity scores(DAS28), blood sedimentation(ESR) and C-reactive protein(CRP) were analyzed. Results: ①Four hundred and forty joints showed synovial thickening, 82 Wri and 328 MCP+PIP. The proportion of blood flow signal detected by cSMI in thickened synovial membranes of Wri was 83.9％, while that of PDUS was 62.5％. The proportion of blood flow signal detected by cSMI in thickened synovial membranes of MCP+PIP was 81.4％, while that of PDUS was 63.7％. The differences of blood flow signal rate between both Wri and MCP+PIP were statistically significant, so was the comparison of two imaging patterns(P＜0.05). ②The differences of grading of PDUS and cSMI between Wri and MCP+PIP were statistically significant(P＜0.05). Compared with PDUS, cSMI could raise the blood flow classification level. ③PDUS and cSMI blood flow signals grading were positively correlated with CRP, ESR and DAS28(P＜0.05). Compared with PDUS, the correlation between cSMI and CRP, ESR and DAS28 increased(P＜0.05). Conclusions: cSMI can more prominently detect the thickened synovial blood flow of RA in the active period, and can also assess the disease activity better.

Key words： Arthritis, rheumatoid Ultrasonography

Received: 12 January 2018

PACS:	Ｒ593.22
	Ｒ445.1

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	Articles by authors
	QI Qing-hua
	WANG Jun-kui
	ZHOU Yuan-yuan
	ZENG Qing-hu
	WU Zhi-bin
	ZhANG Rui-fang

Cite this article:

QI Qing-hua,WANG Jun-kui,ZHOU Yuan-yuan, et al. Evaluation of rheumatoid arthritis in the active period by color superb microvascular imaging[J]. JOURNAL OF CHINA MEDICAL IMAGING, 2018, 29(12): 893-896.

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http://www.jccmi.com.cn/EN/DOI:10.12117/jccmi.2018.12.014 OR http://www.jccmi.com.cn/EN/Y2018/V29/I12/893

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