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| The value of multimode magnetic resonance imaging in differential diagnosis of benign and malignant breast tumors |
| LIU Xue-jing, SHAN Yan-na, HAN Zhi-jiang |
| Department of Radiology, Hangzhou First People's Hospital, Hangzhou 310006, China |
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Abstract Objective: To explore the value of different sequences of 3T magnetic resonance in the differential diagnosis of benign and malignant breast tumors. To optimize the diagnostic performance of DCE-MRI and DWI by the threshold ADC values. Methods: A retrospective analysis of preoperative MRI images of 573 cases with 608 histopathologically verified breast lesions by surgery or biopsy were conducted. A reading method that adapted ADC thresholds to the assigned BI-RADS classification was developed. Sensitivity, specificity, diagnostic accuracy and the area under the curve(AUC) were calculated. BI-RADS-adapted reading was compared with previously published reading methods such as T1WI and T2WI, DWI, T1WI, T2WI and DWI, DCE-MRI in the same population. Result: The sensitivities of T1WI and T2WI, DWI, T1WI, T2WI combined with DWI, DCE-MRI and DCE-MRI combined with DWI were 78.2%, 66.2%, 92.4%, 78.4% and 94.9% respectively. And the specificities were 79.7%, 97.5%, 67.6%, 99.1% and 81.1%, respectively. The AUC was 0.783, 0.846, 0.909, 0.923 and 0.399, respectively. Conclusion: Non-enhanced sequences of 3T magnetic resonance have high sensitivity and low specificity, but it still has some clinical significance when the patient cannot do the DCE-MRI. Multi-parametric breast 3T MRI with BI-RADS-adapted reading improves diagnostic accuracy.
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Received: 21 August 2017
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2018, Vol. 29 
