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| The clinical value of Doppler ultrasound monitoring myocardial performance index in growth restriction fetuses |
| ZHANG Li-na, WU Qing-qing, HAN Ji-jing, SUN Li-juan, LI Zhen, ZHANG Na |
| Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100026, China |
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Abstract Objective: To discuss the clinical value of Doppler ultrasound monitoring myocardial performance index in growth restriction fetuses. Method: A total of 173 cases including 75 early-onset fetal growth restriction(FGR) and 98 late-onset fetal growth restriction(FGR)(divided by 32 weeks of gestation) were recruited from January 2016 to January 2018. They underwent ultrasound examinations in our hospital and were followed up to the pregnancy outcome. The normal controls included 100 cases with <32 weeks and ≥32 weeks respectively. Fetal growth, structural abnormalities, umbilical artery(UA), ductus venosus(DV), middle cerebral artery(MCA) and myocardial performance index(MPI) were monitored and recorded routinely by Doppler ultrasound. The pregnancy outcomes of all cases were followed up. The study groups were divided into adverse and good pregnancy outcome groups. Result: ①The 95th percentile of normal fetuses before/after 32 weeks were 0.50 and 0.52 respectively. ②Compared with normal controls, Early-onset FGR fetuses had increased UA pulsatility index(PI), DV-PI and MPI while decreased parameters including DV-a, MCA- PI and Cerebro-placental Doppler Ratio(CPR). Moreover, increased MPI and decreased MCAS and MCA-RI were found in late-onset FGR cases. ③Compared with good pregnancy outcome group, adverse outcomes in early-onset FGR had increased UA-PI, MCAS, and MPI while decreased MCAD, MCA-RI, and CPR. Moreover, only increased MPI were found in late-onset FGR cases. Conclusion: Doppler ultrasound could diagnose early-onset FGR by monitoring blood flow spectrum changes of UA, MCA, DV and detect late-onset FGR only by the reduction of MCAS and MCA-RI. However, MPI has a high clinical value in the diagnosis and prediction of the prognosis of FGR with different types.
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Received: 15 October 2018
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2019, Vol. 30 
