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Marker of abnormal invasive placenta by ultrasound: “Lacunae” |
ZHANG Jun-ling, LI He-zhou, LI Jie, LI Chun-ling, HAN Rui-zheng |
Department of Ultrasound, Third Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China |
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Abstract Objective: The ultrasonic feature of lacunae in abnormal invasive placenta was investigated and its value was further discussed. Methods: We evaluated 76 women with sonolucent spaces within the prenatal placenta. We recorded the number and the size of the sonolucent spaces, and the velocity of blood flow in them. Meanwhile, we observed the retroplacental sonolucent zone, myometrial thickness, and subplacental blood flow. These patients were then prospectively followed until delivery. According to the follow-up results, they were divided into placenta implantation group and non-implantation group for statistical analysis. Results: Postpartum examination revealed that 36 of the patients had abnormal invasive placenta, while the remaining 40 did not. Patients with abnormal invasive placenta had multiple and large irregular lacunae, and had higher velocity of blood flow in lacunae than those without. The higher the velocity of blood flow in lacunae, the greater the chances of abnormal invasive placenta. By applying the Youden index, the velocity of blood flow in lacunae of 10 cm/s could be considered a cut-off point to diagnose abnormal invasive placenta, with both good sensitivity(89%) and specificity(95%). Conclusion: Lacunae with flow higher than 10 cm/s can be a marker of abnormal invasive placenta for prenatal diagnosis by ultrasound.
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Received: 21 November 2018
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