mono和bi拟合方法对乳腺病变IVIM参数的影响

doi:10.12117/jccmi.2019.02.006

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Abstract Objective: To investigate the difference of parameters from mono and bi based intravoxel incoherent motion(IVIM)-deprived algorithm in breast lesions, and the value in differential diagnosis of benign and malignant breast lesions. Methods: IVIM-MR parameters from a total of 58 breast lesions(27 benign and 31 malignant lesions) were taken from 54 female, including D value, D* value and f value generated and measured by two fitting methods. SPSS 22.0 statistical software was used to compare the coefficient of variation of the parameters measured by two fitting methods, and investigated the difference between mono and bi based IVIM fitting methods. The diagnostic performance in differentiating benign and malignant breast lesions was also compared between mono and bi fitting methods. Results: The coefficient of variation of IVIM parameters by mono fitting method was less than bi from breast lesions. There were significant differences for D and D* values between mono and bi in breast lesions, but the f value was not. The values of D and D* were statistically different by mono fitting method in benign and malignant breast lesions, and the D values on bi fitting method was also so. The area under curve for D value measured by mono fitting method was larger than bi in differentiating benign and malignant breast lesions. Conclusion: Compared with the bi fitting method, mono fitting method is more valuable for the differential diagnosis of benign and malignant breast lesions, and is more suitable for IVIM parameter measurement of breast lesions.

Key words： Breast diseases Magnetic resonance imaging

Received: 24 February 2018

PACS:	Ｒ655.8
	Ｒ445.2

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	Articles by authors
	WEI Qing-shun
	LU Dong-mei
	LIU Yu-lin
	YE Jian-jun
	NIU Juan-qin
	CHEN Gang
	YANG Xiao-ping

Cite this article:

WEI Qing-shun,LU Dong-mei,LIU Yu-lin, et al. Comparison of mono and bi fitting method based IVIM imaging in breast lesions[J]. JOURNAL OF CHINA MEDICAL IMAGING, 2019, 30(2): 98-101.

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http://www.jccmi.com.cn/EN/10.12117/jccmi.2019.02.006 OR http://www.jccmi.com.cn/EN/Y2019/V30/I2/98

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