Abstract Objective: To investigate the value of division of sella region and imaging features(CT, MRI) in the differential diagnosis of benign and malignant sellar space-occupying lesions. Methods: A retrospective analysis was made of 151 cases of sellar space-occupying lesions confirmed by surgery and pathology. The imaging features of lesions in the intrasellar, suprasellar, parasellar and mixed areas were analyzed statistically. The value of division of sella region and imaging features in the differential diagnosis of the sellar space-occupying lesions was discussed. Results: The partition value: Among 151 cases of sellar lesions, benign lesions(75%, 113/151) were significantly higher than malignant lesions(25%, 38/151), 22, 25, 42 and 62 cases in intrasellar, suprasellar, parasellar and mix regions respectively. There were significant differences in the distribution of benign and malignant lesions in sellar region(χ2=6.670, P=0.036<0.05), the highest proportion of intrasellar, suprasellar and parasellar were pituitary adenoma, craniopharyngioma and meningioma, the difference of lesions involving single and mixed region was statistically significant(χ2=10.246, P=0.001<0.01), lesions involving only a single zone(66%, 75/113) were significantly more than the mixed zone(34%, 38/113) in 113 benign cases, the lesions involving the mixed area(63%, 24/38) were significantly more than those in the single region(37%, 14/38) in 38 cases of malignant lesions. The imaging features: benign and malignant lesions had statistical significance differences in location, size, shape, boundary and bone destruction. There was no significant differences in age, sex, tumor characteristic, calcification, presence of pituitary, internal carotid artery and cavernous sinus invasion or wrapping. Conclusion: The distribution and imaging features of the sellar region space-occupying lesions have certain characteristics, which is of high value in the differential diagnosis of the sellar region space-occupying lesions.
ZHAO Jie,LIU Yong,SONG Zhen-yu. Diagnostic value of division of sellar region combined with imaging feature in sellar space-occupying lesions[J]. JOURNAL OF CHINA MEDICAL IMAGING, 2019, 30(4): 234-237.
