不同分子亚型乳腺癌超声造影特征及定量参数对比研究

doi:DOI:10.12117/jccmi.2019.04.009

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Abstract Objective: To investigate the difference of ultrasonographic features and quantitative parameters of different molecular subtypes of breast cancer. Methods: Preoperative ultrasonography was performed in 94 patients with breast cancer confirmed by pathology, and the characteristics and quantitative parameters of ultrasonography in different patients with breast cancer were analyzed. Results: There was a statistically significant difference in the enhancement pattern and the expansion of the enhancement range between the luminal epithelia and non-luminal epithelia(P<0.05), which the luminal epithelia mainly showed fast forward and slow backward and non-luminal epithelia mainly showed fast forward and backward and expansion of scope. In the enhanced mode, fast forward and slow backward were more common in Luminal A, and fast forward and fast backward were more common in Her-2 over-expression and basal-like. High enhancement was dominant in basal-like, high enhancement was also found in Luminal B and Her-2 over-expression, but other enhancement levels were also found. The unclear boundary was more common in Her-2 over-expression. The filling defects were more common in Luminal B and Her-2 over-expression. Expansion of scope was more common in basal-like. In the quantitative parameter index, the ascending branch slope of Luminal B was higher than that of Luminal A, the ascending branch slope of Her-2 over-expression was higher than that of Luminal A, the area under the curve was larger than that of Luminal A, and the ascending branch slope of basal-like was higher than that of Lumin A(P<0.05). Conclusion: There are differences between the characteristics and quantitative parameters of different molecular subtypes of breast cancer, which can be used to provide imaging reference for breast cancer chemotherapy and individual therapy.

Key words： Breast neoplasms Ultrasonography

Received: 24 April 2018

PACS:	Ｒ737.9
	Ｒ445.1

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	Articles by authors
	GAO Jun-xi
	MA Fang-jing
	YANG Lei
	SONG Tao

Cite this article:

GAO Jun-xi,MA Fang-jing,YANG Lei, et al. Comparative study of ultrasonographic features and quantitative parameters of different molecular subtypes of breast cancer[J]. JOURNAL OF CHINA MEDICAL IMAGING, 2019, 30(4): 261-266.

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http://www.jccmi.com.cn/EN/DOI:10.12117/jccmi.2019.04.009 OR http://www.jccmi.com.cn/EN/Y2019/V30/I4/261

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