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Differentiation of renal oncocytoma and clear-cell renal cell carcinomas by MSCT |
CHEN Shang-chao1, CHEN Yu1, YANG Yun-jun2, XIA Neng-zhi2, LIN Bo-li2, HUANG Ying-bao2 |
1. Wenzhou Central Hospital, Wenzhou Zhejiang 325000, China;
2. The First Affiliated Hospital of Wenzhou Medical University, Wenzhou Zhejiang 325000, China) |
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Abstract Objective: To discuss the value of 4 phase MSCT in distinguishing renal oncocytoma(RO) from clear-cell renal cell carcinomas(ccRCC). Methods: Eighty masses from 79 patients underwent plain and enhanced CT scans due to renal mass. Twenty-nine cases of RO and fifty cases of ccRCC were confirmed by pathology. The imaging findings of the two groups were retrospectively analyzed. Attenuation values, corrected attenuation values in 4 phases, differences of the attenuation values between cortical phase and nephrographic phase, enhance clearance rates were analyzed by the Student’s t-test in SPSS 19.0 software. Locations, shapes, characteristics of plain scan, degrees of enhancement, patterns of enhancement, differences of the attenuation values between cortical phase and nephrographic phase and segmental enhancement inversions were analyzed by the Fisher’s exact test. Results: There were statistically significant differences between RO and ccRCC in attenuation values and corrected attenuation values in cortical phase, differences of the attenuation values between cortical phase and nephrographic phase, enhance clearance rates(P<0.05). The attenuation values and corrected attenuation values in unenhancement scan, nephrographic phase and excretory phase had no statistically significant differences between RO and ccRCC(P>0.05).There were statistically significant differences between RO and ccRCC in central stellate low densities,degrees of enhancement, homogeneous degree of enhancement, spoke-wheel-like enhancement, differences between the attenuation values in cortical phase and nephrographic phase and segmental enhancement inversions(P<0.05). Positions, shapes, calcifications, flocculent and streaky shadowings around the lesions had no statistically significant differences between RO and ccRCC(P>0.05). Conclusion: MSCT shows important value in preoperative distinguishing RO from ccRCC. The attenuation values and corrected attenuation values in cortical phase, differences between the attenuation values in cortical phase and nephrographic phase, enhancement clearance rates, central stellate low densities, degrees of enhancement, homogeneous degree of enhancement, spoke-wheel-like enhancement, differences between the attenuation values in cortical phase and nephrographic phase and segmental enhancement inversions can contribute to the differentiation of the RO and ccRCC.
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Received: 23 May 2019
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