应用全模型迭代重建技术的低剂量冠脉CTA在疑似冠心病患者中诊断价值的初步研究

doi:DOI:10.12117/jccmi.2020.04.006

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Abstract Objective: To evaluate the image quality of low-dose coronary CTA combined with iterative model reconstruction(IMR) in coronary arteries and its diagnostic value for coronary stenosis in patients with suspected coronary heart disease. Methods: Eighty patients with suspected coronary heart disease who underwent coronary CTA and the catheter coronary angiography(CAG) in our hospital were analyzed retrospectively. The image quality of each coronary artery was divided into 4 grades. Coronary angiography showing coronary artery luminal diameter reduction>50% as positive standard, the sensitivity, specificity, positive predictive value(PPV), negative predictive value(NPV) and accuracy of coronary CTA in the diagnosis of coronary artery stenosis were analyzed at the level of coronary artery segment and main artery. Patients were divided into two groups according to the Agaston score(group A <400, group B≥400). The difference in diagnostic efficacy between the two groups was compared. Results: At the segment level, 98.1% of the coronary images were qualified, and the sensitivity, specificity, PPV, NPV and accuracy of CTA were 93.2%, 98.0%, 91.3%, 98.4% and 97.1% respectively. At the level of main artery, 96.6% of coronary images were qualified, and the sensitivity, specificity, PPV, NPV and accuracy of CTA were 84.6%, 93.0%, 88.9%, 90.1% and 89.6%, respectively. There were significant differences in specificity, PPV and accuracy between groups A and B(99.2% & 91.8%, 95.7% & 84.2%, 97.9% & 93.7%, P<0.05). Conclusions: Low-dose coronary CTA combined with IMR can obtain satisfactory image quality and has high diagnostic accuracy for coronary artery stenosis. However, the diagnosis of severely calcified segments is still limited.

Key words： Coronary disease Tomography, spiral computed Angiography

Received: 18 July 2019

PACS:	Ｒ543.3
	Ｒ814.42
	Ｒ814.43

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	LIU Xin
	YANG Lin-lin
	WANG Yi-jing
	GAO Si-zhe
	MA Yue
	HOU Yang

Cite this article:

LIU Xin,YANG Lin-lin,WANG Yi-jing, et al. A preliminary study on the diagnostic value of iterative model reconstruction technique combined with low-dose coronary CTA in patients with suspected coronary heart disease[J]. JOURNAL OF CHINA MEDICAL IMAGING, 2020, 31(4): 252-257.

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http://www.jccmi.com.cn/EN/DOI:10.12117/jccmi.2020.04.006 OR http://www.jccmi.com.cn/EN/Y2020/V31/I4/252

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