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| HR-MRI study of arterial remodeling in patients with symptomatic basilar atherosclerosis |
| YAN Xue-jiao, TANG Min, ZHANG Dong-sheng, ZHANG Xiao-ling, GAO Jie |
| Department of Magnetic Resonance Imaging, Shaanxi Province People’s Hospital, Xi'an 710068, China |
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Abstract Objective: Using HR-MRI to explore the characteristics of arterial remodeling(including topical and general) in patients with symptomatic basilar atherosclerosis. Methods: Patients with symptomatic basilar atherosclerosis who were included in HR-MRI were divided into two groups according to whether there was infarction in the blood supply area of basilar artery (BA). 3D-VIAST T1WI imaging was used to measure and compare the plaque and wall characteristics of the patients, including plaque burden, plaque area, perivascular area, topical remodeling type and plaque enhancement degree, etc. Patients with plaque but without infarction were normal controls. The BA area and BA diameter were compared among the three groups to observe the difference of BA general remodeling. Results: There were 12 patients in the BA infarction group(plaque number: 19), 15 patients without BA infarction(plaque number: 18) and 17 patients in the normal group; positive remodeling accounted for a large proportion(63%) in the BA infarction group, and the stenosis rate was greater than that of the BA non-infarction group(P=0.029), and there was no difference in the degree of plaque enhancement among the groups; According to the topical remodeling group, the plaque area and plaque burden of the positive remodeling group were larger than those of the non-positive remodeling group(P<0.05). The area and diameter of BA in symptomatic BA plaque groups were larger than those in control group(P<0.05), but there was no difference between the two indicators in the symptomatic BA plaque groups. Conclusion: In symptomatic infarct group, positive remodeling was the main local remodeling of BA plaque, and there was general expansion remodeling in BA of symptomatic BA atherosclerosis.
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Received: 02 November 2019
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2020, Vol. 31 
