核素显像评估不同阶段冠心病患者心脏收缩同步性的研究

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Abstract Objective: To assess the change rule of the cardiac systolic dyssynchrony in patients with coronary heart disease in different stage by gated SPECT myocardial perfusion image(GSMPI). Method: A retrospective analysis was made at 94 cases with GSMPI, including the healthy people(control group, 40 cases), mild myocardial ischemia group(20 cases), moderate myocardial ischemia group(16 cases) and severe myocardial ischemia group(18 cases). The software named Emory Cardiac Toolbox was used to process the data, and the systolic synchrony parameters were acquired, including phase histogram bandwidth(PHB), phase standard deviation(PSD). Myocardial blood flow parameters included summed stress score(SSS), summed rest score(SRS) and summed difference score(SDS). The difference of PHB, PSD between the myocardial ischemia group and the control group separately were compared. The difference among the three myocardial ischemia groups were studied. The relationship among the PHB, PSD and SSS and SDS were analyzed. Result: For PHB and PSD, there’s no obvious difference between the mild myocardial ischemia group and the control group(P>0.05); There have significant different exits among moderate, severe myocardial ischemia group and the control group(P<0.05). PHB and PSD were both positively correlated obviously with SSS and SDS. Conclusion: The progress of cardiac systolic dyssynchrony happened with the aggravation of myocardial ischemia in patients with coronary heart disease. GSMPI can supply systolic synchrony and myocardial ischemia parameters by “one stop”, has certain application value in choosing the early coronary heart disease patients with cardiac systolic dyssynchrony.

Key words： Coronary disease Radionuclide imaging

Received: 17 April 2017

PACS:	Ｒ543.3
	Ｒ817.4

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	Articles by authors
	LI Ting
	LI Jian-ming
	WANG Jiao
	CHEN Yue
	LU Ru-ming
	LIANG Yu

Cite this article:

LI Ting,LI Jian-ming,WANG Jiao, et al. Research of radionuclide imaging on assessing ventricular systolic synchrony in patients with #br# coronary heart disease in different stage[J]. JOURNAL OF CHINA MEDICAL IMAGING, 2018, 29(2): 97-101.

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http://www.jccmi.com.cn/EN/ OR http://www.jccmi.com.cn/EN/Y2018/V29/I2/97

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