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| Prostatic neoplasms; Magnetic resonance imaging |
| WANG Zhong-juan, WU Wen-juan, JIANG Chun-juan, WANG Hua |
| Department of Radiology, the Second People’s Hospital, Wuxi Jiangsu 214002, China |
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Abstract Objective: To explore the diagnostic value of apparent diffusion coefficient(ADC) and magnetic resonance dynamic contrast-enhanced imaging(DCE-MRI) in prostate cancer(PCa) and seminal vesicle invasion(SVI). Methods: DWI and DCE-MRI data of 50 cases of pathologically proved PCa was retrospectively analyzed. DWI and ADC map appearance of all Pca foci, SVI and normal seminal vesicle(NSV) were analyzed. And their ADC mean values were measured. The styles of the SI-T were analyzed. Tmax, SImax%, Rmax were calculated. Sensitivity, specificity and accuracy were calculated also. Results: All PCa foci and SVI showed high signal intensity on DWI and low signal intensity on ADC map. The mean ADC values of PCa, SVI, NSV were (0.928±0.128)×10-3 mm2/s, (0.965±0.161)×10-3 mm2/s, (2.785±0.235)×10-3 mm2/s respectively. There was statistical significance among the SVI and NSV(t=20.896, P<0.05). There was no statistical significance among the PCa and SVI(t=2.013, P>0.05; F＝1.423, P>0.05). PCa and SVI in DCE-MRI showed early enhanced, the common styles of SI-T curves were rapidly ascending followed with descending curve. The value of Tmax, SImax%, Rmax in SVI and NSV were statistical significant(t＝-9.05, 4.75, 16.95, P＜0.05). DWI combined DCE-MRI can obviously increase the diagnostic sensitivity, specificity and accuracy. Conclusion: ADC combined with DCE-MRI might be helpful in diagnosis of PCa and SVI.
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Received: 11 April 2017
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