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Imaging and clinicopathological features of extrapleural solitary fibrous tumors: report of eleven cases and literature review |
HAN Jia-yue, SHA Lin, HAN Ning, YU Yang |
Department of Radiology, the Second Affiliated Hospital of Dalian Medical University, Dalian Liaoning 116027, China |
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Abstract Objective: To analyze the CT and MRI and clinicopathological features of extrapleural solitary fibrous tumors(ESFT), and to improve the level of recognition and diagnosis of this disease. Methods: Reviewing the literatures in recent years, 11 cases of ESFT confirmed by pathology were retrospectively analyzed, and their clinical, pathological and imaging diagnoses were analyzed and summarized. Results: Among all the eleven cases, 3 cases were in the retroperitoneum, 2 cases in thigh and mediastinum respectively, one in hip, kidney, testis, and pelvis respectively. A total of 13 lesions were detected in 11 cases. All 13 lesions were shown as round or lobulated masses with maximum diameter ranged from 2.5 cm to 24.8 cm. Ten lesions appeared cystic degeneration or necrosis, 1 with calcification on CT, 2 lesions with cystic degeneration or necrosis had low signal on T1WI and mixed signal on T2WI, 9 lesions showed moderate or marked enhancement in arterial phase and delayed enhancement, 4 lesions showed slight enhancement in arterial phase and delayed enhancement, 6 lesions were enhanced to show the surrounding and internal vessels of the focus. Immunohistochemical staining results were shown as follow: bcl-2+(12/12), Vimentin+(9/12), CD34+(11/12), CD117(0/12), SMA(0/12), CK(0/12), S-100(0/12) were all negative. Conclusion: The imaging features of ESFT have a certain diversity, and the prospective diagnosis is not easy. If it is found that the solitary mass with clear boundary, enhanced scan showed continuous or delayed enhancement and see the circuitous vessels, should take into account the tumor, and the definite diagnosis needs to rely on immunohistochemistry.
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Received: 12 June 2017
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