Abstract:Objective: The pathohistology of retroperitoneal neurogenic tumor is multiplex, by the analysis of the tumor’s ultrasonography, we try to discriminate the benign tumor from the malignant tumor and evaluate the ultrasonographic imaging features of retroperitoneal neurogenic tumor. Methods: The ultrasonographic imaging features of 25 cases were analyzed and compared with the results of pathology. Results: The common sites of retroperitoneal neurogenic tumor included spinal roots and the area surrounding kidney and adrenal; The tumors were large, mainly hypoechoic. Thirteen cases were cystic, 13 cases had calcification; No difference between the benign and malignant tumors on the shape and boundary(P>0.05); No difference between the benign and malignant tumors on the color Doppler flow imaging(CDFI)(P>0.05); The diameter of the malignant tumor was much larger than that of the benign tumor(P<0.025, a=0.05). Close and tiny calcification was the characteristic of the neuroblastoma, the CDFI of pheochromocytoma was plentiful, associated with dispersed small cysts and there were its characteristics. Conclusions: The ultrasonograhic features of retroperitoneal neurogenic tumor is not characteristic and ultrasonograhic accuracy was not high; It is not reliable to distinguish the benign and malignant tumors by the shape, boundary or CDFI only.