Clinical and MRI diagnosis of hemimegalencephaly: report of 5 cases with literature review
LIU Zhai1, HE Li1, WANG Wei-xiu2, REN Qing-yun1
1. Department of Radiology, the First Hospital of Hebei Medical University, Shijiazhuang 050031, China;2. Children’s Hospital of Hebei Province, Shijiazhuang 050031, China
Abstract：Objective: To investigate the clinical and MRI features of hemimegalencephaly(HME). Methods: The clinical and MRI findings of 5 cases with HME were reviewed retrospectively, at the same time literature review was carried out. Results: Epilepsy was found in 3 cases, hemi-hypertrophy of extremities found in 3 cases, mental retardation in 2 cases. MRI showed enlargement of the affected cerebral hemisphere, apparent thickening of the grey matter, and poor grey/white differentiation in all 5 cases. Involvement of left cerebral hemisphere in 3 cases and right hemisphere 2 cases. Enlargement of the ipsilateral ventricle was seen in all cases, straightening of the forntal horn of the ipsilateral ventricle in 2 cases and colpocephaly in 1 case. Three cases had hyper-intensity in the white matter of the affected hemisphere. Conclusion: There is characteristic MRI features of HME. MRI demonstrates diffuse hypertrophy of the affected hemisphere, ipsilateral ventricle dilatation, thickened cortex, and hyperintensity of the white matter.
刘 斋;何 丽;王伟秀;任庆云. 半侧巨脑畸形的临床及MRI诊断（附5例报告并文献复习）[J]. , 2014, 25(8): 538-541.
LIU Zhai;HE Li;WANG Wei-xiu;REN Qing-yun. Clinical and MRI diagnosis of hemimegalencephaly: report of 5 cases with literature review. , 2014, 25(8): 538-541.
2014, Vol. 25 
