Abstract：Objective: To explore clinical application value of prenatal ultrasound in diagnosis of fetal heterotax syndrome with segmental analysis, to compare the results of pathological anatomy. Methods: We compared relevance ratio between February 2011 to December 2012 without using segmental analysis and January 2013 to March 2015, 21 fetus with heterotax syndrome confirmed by prenatal ultrasound were analyzed retrospectively through segmental analysis. We also compared the prenatal ultrasonographic characteristics and pathologic autopsy after induced labor. Results: During the period of January 2013 to March 2015, 21 fetuses with heterotax syndrome were diagnosed, and proved by autopsy. Sixteen fetuses had right isomerism with complex cardiac anomalies, juxtaposition of inferior vena cava and abdominal aorta, abnormal position of the stomach, 15 fetuses with asplenia, 1 fetus with spleen dysplasia; 5 fetuses had left isomerism with interruption of inferior vena cava with azygos continuation, 3 fetuses with complex cardiac anomalies, 2 fetuses with normal cardiac structure, 2 fetuses with atrioventricular block. Eighteen fetuses were confirmed by pathological anatomy after induced labor. While in February 2011 to December 2012, without using segmental analysis, 4 fetuses with heterotax syndrome were missed diagnosis compared with autopsy, only 1 case was detected by prenatal ultrasound. Conclusion: Segmental analysis for prenatal ultrasound can significantly reduce the misdiagnosis rate of fetal heterotax syndrome, in favor of the prenatal counseling and clinical treatment of decision-making in the perinatal period.
何晓琴，钟晓红. 产前超声“节段分析法”诊断胎儿内脏异位综合征[J]. 中国临床医学影像杂志, 2015, 26(11): 808-811.
HE Xiao-qin, ZHONG Xiao-hong. Segmental analysis for prenatal ultrasound in diagnosis of fetal heterotax syndrome. JOURNAL OF CHINA MEDICAL IMAGING, 2015, 26(11): 808-811.
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