Abstract：Objective: To analyze the clinical and MRI quantitative changes of primary intracranial hypotension syndrome, and to improve the understanding and diagnostic accuracy of the disease. Methods: Twenty-four cases of primary intracranial hypotension syndrome were retrospectively analyzed. All the patients underwent MRI plain scan and enhanced scan, of which 5 cases were examined by MRV. Quantitative measurements included dural thickness, pituitary height, transverse diameter of the third ventricle, the width of the central sulcus, the distance between the body of che pons and the width of the torcular herophili. Results: All cases had postural headache, lumbar puncture cerebrospinal fluid pressure 0～60 mmH2O, MRI enhanced scan showed diffuse and symmetrical linear enhancement. Dural thickness, pituitary height were negatively correlated with cerebrospinal fluid pressure(P<0.05), the third ventricle diameter, central sulcus width, mammillary body pons spacing were positively correlated with cerebrospinal fluid pressure(P<0.05), and the width of torcular herophili was not correlated with cerebrospinal fluid pressure(P>0.05). Conclusion: The clinical and MRI features of primary intracranial hypotension syndrome have some characteristics, the dural thickening, pituitary enlargement, ventricle, cerebral sulcus narrowing and cerebral ptosis degree can be used as objective evaluation indexes in clinical treatment.
吴立业，刘 军. 原发性低颅压综合征的临床及MRI定量分析[J]. 中国临床医学影像杂志, 2018, 29(4): 242-245.
WU Li-ye, LIU Jun. Clinical and MRI quantitative analysis of primary intracranial hypotension syndrome. JOURNAL OF CHINA MEDICAL IMAGING, 2018, 29(4): 242-245.
