Abstract：Objective: To investigate interobserver agreement and diagnosis value of multiparametric MRI(mp-MRI) using vesical imaging-reporting and data system(VI-RADS) in detecting muscle-invasiveness of bladder cancer. Methods: Retrospective analysis of 99 patients(109 tumors in total) with pathologically confirmed bladder cancer was made in this study. The tumors was classified as non-muscle invasive bladder cancer(NMIBC) with stage T1 or lower and muscle invasive bladder cancer(MIBC) with stage T2 or higher. The mp-MRI images of tumors were scored by two radiologists independently with blind method by using VI-RADS. Interobserver agreement was evaluated by using Kappa test. Receivers operating characteristic(ROC) curves were used to describe the diagnostic efficiency of two radiologists. Results: Interobserver agreement of VI-RADS was good(Kappa value=0.721, P<0.001). According to ROC analysis, VI-RADS score 4 was found to be the best cut-off levels for discriminating NMIBC from MIBC by two radiologists, with the AUC of 0.912 and 0.925, the sensitivity of 76.2% and 71.4%, the specificity of 95.5% and 95.5%, the positive predictive value of 80.0% and 79.0%, the negative predictive value of 94.4% and 93.3%, respectively． Conclusion: The VI-RADS shows good consistency and stability for evaluation bladder cancer. Futhermore, VI-RADS demonstrates a good accuracy in the detection of muscle-invasiveness of bladder cancer, and provides a high specificity and negative predictive value.
张添辉，古志聪，姚 纯，朱文标，程亚宝，张文巨，冯志强，范伟雄. 多参数磁共振成像VI-RADS评分对膀胱癌肌层浸润诊断价值的初步研究[J]. 中国临床医学影像杂志, 2019, 30(8): 569-573.
ZHANG Tian-hui, GU Zhi-cong, YAO Chun, ZHU Wen-biao, CHENG Ya-bao, ZHANG Wen-ju, FENG Zhi-qiang, FAN Wei-xiong. Diagnostic value of multiparametric MRI using vesical imaging reporting and data system in detecting muscle-invasiveness of bladder cancer. JOURNAL OF CHINA MEDICAL IMAGING, 2019, 30(8): 569-573.
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