Abstract：Objective: To explore the value of ultrasound elastography in determining the degree of chronic nephropathy in children. Methods: Based on the pathological results of renal puncture biopsy, 40 patients with chronic kidney disease(CKD) and 40 normal control cases were collected. Both the ratio of male to female was 1∶1. Firstly, two-dimensional ultrasound images were collected to record the location, size, shape, echo, boundary and blood flow signal distribution of the Kidney. After the image was stabilized, the elastic imaging mode was activated, and real-time elastic imaging was performed on the right lower pole of the kidney. Young’s modulus value of the renal cortex was measured repeatedly within 5~7 cm depth and the region of interest(ROI) diameter within 5~7 mm, and the difference was compared after quantitative analysis. Results: The Young’s modulus value of renal cortex in CKD patients who were diagnosed by biopsy was (6.72±1.93) kPa, compared with the value of (3.19±0.62) kPa in control group. The difference was statistically significant(P<0.05). It indicates that the hardness of the kidney of the sick child is greater than the healthy child. Conclusion: Real-time shear wave ultrasound elastography can quantitatively detect the Young’s modulus of renal cortex in children patients with CKD and healthy children, and it is concluded that the Young’s modulus of renal cortex in children with CKD is larger than healthy children. Shear wave ultrasound elastography can help clinicians in the diagnosis and treatment of children with CKD.
高 峰，蒋苏齐. 实时剪切波弹性成像技术在儿童慢性肾病中的应用价值及临床相关性研究[J]. 中国临床医学影像杂志, 2019, 30(8): 574-577.
GAO Feng, JIANG Su-qi. Study on the application value of shear wave ultrasound elastography in the diagnosis of chronic nephropathy in children. JOURNAL OF CHINA MEDICAL IMAGING, 2019, 30(8): 574-577.
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